Feb 04–07, 2024 | Fairmont Hotel Vancouver, Vancouver, BC, Canada
Scientific Organizers:
Giles S.H. Yeo, Karine Clément, and Murielle M. Véniant-Ellison

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Scientific Organizers: Giles S.H. Yeo, Karine Clément, and Murielle M. Véniant-Ellison
Giles S.H. Yeo
Karine Clément
Murielle M. Véniant-Ellison
***Meeting program subject to change.
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Sunday, February 4, 2024
Monday, February 5, 2024
Session Chair
Session Chair
Leveraging Genetics to Understand Metabolic Disease
Optimizing Precision Medicine Across Diverse Ethnicities
Session Chair
Metabolic Disease in the Context of Genetic Diversity
Population Specific Precision Medicine for Metabolic Disease
Short Talk: Short Talk: Ectopic ASIP Expression as a Monogenic cause of Childhood Obesity through Possible Interaction with the MC4R Pathway
Short Talk: Short Talk: Obstructive Sleep Apnea is Associated with Increased Genetic Risk of Incident Diabetes Mellitus: the Hispanic Community Health Study/Study of Latinos
Session Chair
The Intestinal MC4R Promotes Weight Loss by Reducing Caloric Intake and Increasing Energy Expenditure
Orthopedia Regulates Mc4r Transcription and Human Obesity Risk
Different Roles in Food Intake Regulation for Distinct Populations of Dorsal Vagal Complex Glp1r Neurons
Functional Genomics of Human Metabolic Disease at Single Cell Resolution
Presence of Beta-Arrestin-2 is Required for Melanocortin 4 Receptor-Mediated Metabolic Effects
CTRP6-Mediated Suppression of Macrophage M2 Phenotype: Implications for Obesity-Associated Inflammation
Glial Support of Neurovascular Function in Obesity
Session Chair
Microbiota and Stress
Ultra-Processed Foods and Obesity
Intertissue Communication Following an Exercise Bout in Type 2 Diabetes
Short Talk: Short Talk: Exploring Body Composition and Energy Expenditure Changes After Diet Restriction and Pharmacologically Induced Weight loss in a Göttingen Minipig Model of Obesity
Short Talk: Short Talk: Semaglutide and Lanifibranor Differentially Alter MASH and Liver Fibrosis in Diet-induced Obese Hamsters With or Without Free Access to Alcohol
Tuesday, February 6, 2024
Session Chair
Mapping the Feeding Circuitry of the Human Hypothalamus
Hypothalmic Nutrient Sensing
Hypothalamic Mechanisms of Obesity
Hindbrain Circuits that Control Feeding
Targeting Hypothalamic Weight-Loss Circuits
Short Talk: Short Talk: Glp1r-expressing LepRb Neurons of the Dorsomedial Hypothalamic Nucleus Inhibit AgRP Neurons and Suppress Body Weight
Short Talk: Short Talk: Molecular Connectomics Reveals a Glucagon-Like Peptide 1 Sensitive Neural Circuit for Satiety
Panelist
Panelist
Panelist
Panelist
Panelist
Session Chair
Astrocyte Lipid Metabolism: How it Shapes your Appetite and Energy Balance
Disrupted Circadian Glucocorticoid Rhythms and High Fat Diet Drive Obesity through Distinct Mechanisms
HYPOMAP: A Spatio-cellular Atlas of the Human Hypothalamus
Novel Lipidated Interleukin-22 Reduces Body Weight, Lowers Plasma Glucose, and Improves Cardio-Metabolic Risk Factors in Mice
Unlocking Metabolic Benefits Effects of Sodium-Glucose-Co-Transporter-4 (SGLT4) Inhibition: From Mouse Studies to Clinical Translation
Adipocyte Autophagy in the Control of Obese Adipose Tissue Inflammation and Remodelling
Dissecting Adipose Tissue at Single-Cell Resolution During Metabolic Disease Development
Disruption of Mesoderm Specific Transcript (Mest) in Female Mice Alters Spontaneous Physical Activity and Protects Against Diet-induced Obesity
Session Chair
Cardiometabolic Risk, Insulin Resistance and Obesity
Why does Obesity Cause Diabetes?
Short Talk: Short Talk: Damaging Mutations in LXRalpha Uncouple Lipogenesis from Hepatotoxicity and Implicate Hepatic Cholesterol Sensing in Human Liver Health
Short Talk: Short Talk: Mechanisms of Prediabetes Remission in People without Weight Loss and with Weight Gain
Short Talk: Short Talk: G Proteins Gsa and Gq/11 in the Paraventricular Nucleus of the Hypothalamus (PVN) Mediate Distinct Cardiovascular and Metabolic Responses to Melanocortins
Short Talk: Short Talk: Body Weight-independent Anti-inflammatory Effects of GLP-1R Agonists via the Neuronal GLP-1R
Wednesday, February 7, 2024
Session Chair
Precision Obesity Medicine in Practice
The GLP1/GIP System in Obesity Management
Insights From Genetic and Observational Studies in South Asian Populations
Personalized Nutrition in Obesity Management
Short Talk: Short Talk: GABAergic GIPR-expressing Neurons are Required for the Body Weight Reduction caused by Dual Incretin Agonists
Physician-in-Chief, Chair, and Professor
Section Chief: Diabetes Molecular Genetics Section
VP & Distinguished Scientist
Reader & Associate Professor
Session Chair
Kidney Disease and Obesity
Targeting GLP-1/GIPR in a Novel Bispecific Mechanism to Advance a Longer-acting Therapy for Weight Loss: Maridebart Cafraglutide (AMG 133)
Short Talk: Short Talk: Nrac Regulates Fatty Acid Import in Adipocytes via Regulating CD36 Localization
Short Talk: Short Talk: Dual Energy Expenditure and Appetite Control by Insulin-Sensitizing NK2R Agonism
Short Talk: Short Talk: Alpha-melanocyte Stimulatory Hormone (α-MSH): A Novel Mediator of Skeletal Muscle Glucose Uptake in Humans
Thursday, February 8, 2024
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