Apr 09–12, 2024 | Fairmont Banff Springs, Banff, AB, Canada
Scientific Organizers:
Kate L. Jeffrey, Ramnik Xavier, and Xu Zhou

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Scientific Organizers: Kate L. Jeffrey, Ramnik Xavier, and Xu Zhou
Kate L. Jeffrey
Ramnik Xavier
Xu Zhou
***Meeting program subject to change.
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Tuesday, April 9, 2024
Wednesday, April 10, 2024
Variants Linked to Functional Phenotypes and Causal Mechanisms in Relevant Cell Types
Activating and Inhibitory Innate Immune Receptors in Neurodegeneration
Talk Title to be Announced
Short Talk: Short Talk: Cellular RNA Interacts with MAVS to Promote Antiviral Signaling
Short Talk: Short Talk: Spatial Gradients of Pathogen-sensing Capability Confer a Tiered Tissue Self-Defense System
Tissue Stiffness is a Fundamental Regulator of NLRP3 Inflammasome Activities
Mechanistic Basis for Potassium Efflux Driven Activation of the Human NLRP1 Inflammasome
GSDME Promotes PAD4 Activation and DNA Externalization from Apoptotic Neutrophils
Interaction Between NLRP11, CASP4, and LPS in the Context of the Innate Immune Response to Bacterial Pathogens
Sterol-izing Immunity: Cholesterol Control of Mammalian Gasdermins
An Unconventional Mechanism of IL-1b Secretion that Requires Type I IFN in SLE Monocytes
S-palmitoylation of Gasdermins Regulate Their Function in Membrane Pore Formation and Pyroptotic Cell Death
Chromatin Readers and Inflammation
Signaling to Chromatin for Rapid Innate Immunity
Talk Title to be Announced
Epigenetic Regulation of the Host-microbiota Relationship
Thursday, April 11, 2024
Environmental Control of Inflammatory Response
Tissue Tolerance to Infection
Neutrophil Dynamic Behavior
Short Talk: Short Talk: Dissecting a Novel Stem-Cell Defense Mechanism in Early Epithelial-Specific Responses to an Enteric Bacterial Pathogen
Short Talk: Short Talk: Characterization of Interferon-Induced Gene Expression in the Mouse Lung and Liver
Short Talk: Short Talk: High Resolution 3D Spatial-Temporal Mapping of Influenza A Virus Infection and Innate Immune Signaling in Whole Lung Organs Reveals the Early Spatial Interplay of Viral Spread and Host Response
Short Talk: Short Talk: Spatial Transcriptomics Reveals Interaction of Mesothelial Cells with Injury-Derived Osteopontin in Serosal Scarring
Head of Cellular Genetics and Senior Group Leader, Co-Founder and Principal Leader of Human Cell Atlas
VP and Global Head, Immunology Therapeutic Area
Associate Professor
Senior Director, CSO Partner Team
Remote Presentation: Microbial Control of Tissue Threshold of Activation
Unraveling TB Granuloma Phagocyte Heterogeneity
Fibroblasts in Chronic Inflammatory Diseases
Short Talk: Short Talk: Decoding Immune Mediated Circuits Supporting Tissue Physiology
Short Talk: Short Talk: Astrocyte Sensitivity to Nucleic Acid Agonism Contributes to Neurodegeneration in iPSC-Derived Tri-Culture Models of Amyotrophic Lateral Sclerosis
Friday, April 12, 2024
Cell Atlas Mapping of the Immune System Across Organs
SCimilarity Queries Reveal Connections across Macrophage Populations
Decoding the Body Language of Immunity
Short Talk: Short Talk: STING Modulates Golgi pH, Cargo Sorting, and Secretion Through ArfGAP2
Short Talk: Short Talk: Molecular Cartography Reveals Robust, Adaptable, and Resilient Intestinal Networks
Short Talk: Short Talk: Role of a Cellular Circuit Involving IFN-γ / IL-15 Positive Feedback in Establishing Antigen-Non-Specific Immune Memory
Short Talk: Short Talk: A Paradox of Foreign-Specific Regulatory T Cells and a Proposed Resolution by a Lymph Node Microdomain Theory
Immune Checkpoint Molecule Tim-3 Regulates Microglial Function and the Development of Alzheimer’s Disease Pathology
Non-Canonical Type I Interferons are Induced by Cholesterol Restriction and Prime RIG-I-Mediated Antiviral Innate Immune Responses
Cancer and Vascular Immune Assembloids Model the Oncofoetal Niche in the Solid Tumor Microenvironment
Exploring the Role of GPR65-Mediated pH Sensing in Tuning Systemic and Local Immune Responses
TLR4’S Impact on Pcos Outcomes in Letrozole-induced Mouse Model
Mucosal Single-Cell Profiling of Crohn’s-Like Disease of the Pouch Reveals Unique Pathogenesis and Therapeutic Targets
Multi-Antigen Management by Dendritic Cells Within the Melanoma Microenvironment
Engineered Treg Therapies for Inflammatory Disorders
Talk Title to be Announced
Drugging Innate Immunity
Short Talk: Short Talk: Chemical Biology of Extracellular cGAMP Signaling in Health and Disease
Saturday, April 13, 2024
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