Sep 06–09, 2024 | Beaver Run Conference Center, Breckenridge, CO, United States
Scientific Organizers:
Mingjie Zhang and Jin Zhang

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Scientific Organizers: Mingjie Zhang and Jin Zhang
Mingjie Zhang
Jin Zhang
***Meeting program subject to change.
Available Formats: = In Person = On DemandFriday, September 6, 2024
Fundraising
Booking Function
Saturday, September 7, 2024
Session Chair
Phase Separation in Biological Systems
Session Chair
Phase Separation in Protein Kinase Signaling
The Role of Emergent Condensate Properties in Transcription
Phase Separation and Cell Stress Signaling
Short Talk: Scope and Mechanism of Poly(ADP-ribose)-mediated Protein Condensation
Session Chair
Development of a Molecular Tool iDoG to Explore the Physiological Roles of Biomolecular Condensates
Neuronal Aging Leads to Chronic Activation of the Stress Response
Synthetic Biomolecular Condensates Enhance Translation from a Target mRNA in Living Cells
The Role of lncRNAs in Biomolecular Condensation of Leukemia Fusion Oncoproteins
Gain-of-Function RNA Polymerase II Partitioning is a Shared Feature of Diverse Oncogenic Fusions
Biomolecular Condensates as Crucibles of Protein Aggregation
Structures of Biomolecular Condensates by Cryo-ET
TERRA-LSD1 Phase Separation Promotes R-Loop Formation for Telomere Maintenance in ALT Cancer Cells
Session Chair
Passage of HIV Capsids through the FG Phase of Nuclear Pores
Miscibility and Immiscibility of Condensates Control Chromatin Organization and Transcription
Structure-Function Relationships in Mitochondrial Transcriptional Condensates
Short Talk: YAP Signal Integration Through Transcriptional Condensates
Short Talk: RNA in the Regulation of Transcriptional Condensates
Sunday, September 8, 2024
Phase Separation in Synapses
Size Regulation of FUS Condensates
Phase Separation and Circadian Rhythm
Phase Separation in Integrin Signaling
Short Talk: PD-1 Regulates the Formation of Protein Condensates in T-Cell Receptor Signaling
Short Talk: Tuning Epidermal Growth Factor Receptor (EGFR) Condensate Properties Through Adaptor Protein Valency and Competition
Short Talk: Liquid-to-Solid Phase Transition of MEC-2 Condensates is Required for Mechanotransduction During Touch
Panelist
Panelist
Panelist
Panelist
Panelist
Co-Founder & Chief Scientific Officer, Professor
Associate Professor
US Head In Vitro Biology, Integrated Drug Discovery
Associate Professor
Session Chair
Phase Separation in Cell Signaling
Phase Separation in Autophagy
Phase Separation and Cell Signaling at Membrane Interface
Short Talk: Membrane-Associated SCOTIN Condensates in the Regulation of Organelle Stress Response and Dynamics
Monday, September 9, 2024
Session Chair
Harnessing Phase Separation for Drug Development
Discovery of Condensate Modifying Drugs Through AI-Powered Experimental Platform
Applying RNA Binding Proteins and Biological Condensates to Develop Therapeutic Pipelines for Amyotrophic Lateral Sclerosis and Alzheimer’s Disease
TDP-43 Phase Transitions in Neurodegenerative Diseases
Short Talk: Condensate Proteolethargy is a Pathogenic Mechanism in Chronic Disease
Short Talk: G-Quadruplexes Modulate TDP-43 Aggregation In Vitro And In Vivo
Session Chair
Alpha-Synuclein Regulates the Material Properties of Synapsin Condensates in Live Cells
Size-Dependent Functional Transitions in Actin Signaling Protein Condensates
Combining Molecular and Whole-Cell Models to Reveal Design Features Underlying Nucleocytoplasmic Transport
Active RNA Synthesis Patterns Nuclear Condensates
Session Chair
Inflammasomes: Condensates and Ordered Supramolecular Assemblies
High-Fidelity Probing of Intracellular Phase Separation Dynamics
Oncoprotein Transcription Factor MYC Undergoes Phase Separation that Differentially Modulates the Transcriptome
Short Talk: Physical-Chemical Probing Reveals a Networked Nucleolar Structure Funneling Ribosome Biogenesis
Tuesday, September 10, 2024
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