Joint with: The Ubiquitin Family in Biology and Disease
Proximity Based Biology and Therapeutics: Targeted Protein Degradation and Beyond

Feb 23–26, 2026 | Fairmont Banff Springs, Banff, AB, Canada
Scientific Organizers: Neil Bence, Cheryl Arrowsmith, and Amit Choudhary

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Feb 23–26, 2026 | Fairmont Banff Springs, Banff, AB, Canada

Scientific Organizers: Neil Bence, Cheryl Arrowsmith, and Amit Choudhary

Supported by the  Directors' Fund

***Meeting program subject to change.

Available Formats:     = Livestream   = In Person     = On Demand
Monday, February 23, 2026
Registration
4:00–8:00 PM
 Van Horne Foyer
Welcome Mixer
6:00–8:00 PM
 Van Horne Foyer
Tuesday, February 24, 2026
Breakfast
7:00–8:00 AM
 President's Hall
Welcome and Keynote Address
8:00–9:00 AM
 Van Horne A
Ning Zheng, University of Washington
Stuck on You: The Omnipresence of Molecular Glues
Transformation of Drug Discovery and Induced Proximity through AI/ML
9:00–11:15 AM
 Van Horne A
Nicholas F. Polizzi, Dana-Farber Cancer Institute
Designing Biosensors from Scratch Using Principles of Induced Proximity
George M Burslem, University of Pennsylvania
Chemical Tools to Edit Protein Sequences and Post-Translational Modifications
Mikko Taipale, University of Toronto
Navigating the Proteome with Induced Proximity
Short Talk(s) Chosen from Abstracts
Coffee Break
9:30–9:50 AM
 Van Horne Foyer
Poster Setup
11:15–1:00 PM
 Van Horne C
On Own for Lunch
11:15–5:00 PM
Poster Viewing
1:00–10:00 PM
 Van Horne C
Symposia Spotlight: Emerging Technologies and Approaches in Proximity Induction
2:30–4:30 PM
 Van Horne A
Coffee Available
4:30–5:00 PM
 Van Horne Foyer
Novel Induced Proximity based Approaches
5:00–7:00 PM
 Van Horne A
Amit Choudhary, Harvard Medical School
Proximity-Inducing Molecules for Protein Editing
Gerald R. Crabtree, Stanford University
Transcriptional Chemical Inducers of Proximity
Elena De Vita, Queen Mary University of London
Targeted Protein Dephosphorylation vial PHOSTACs
Short Talk(s) Chosen from Abstracts
Social Hour with Dinner
7:00–8:00 PM
 President's Hall
Posters
7:30–10:00 PM
 Van Horne C
Wednesday, February 25, 2026
Breakfast
7:00–8:00 AM
 President's Hall
Leveraging Novel Protein Degradation Machinery for Next Generation Protein Degraders
8:00–11:00 AM
 Van Horne A
Cheryl Arrowsmith, University of Toronto
Increasing the Repertoire of Chemically Recruitable E3 Ligases for Targeted Protein Degradation
Gwenn Hansen, Nurix Therapeutics
Enabling Novel Ligases for Targeted Protein Degradation through DEL based Approaches
Daniel K Nomura, University of California, Berkeley
Enabling Novel Ligases
Short Talk(s) Chosen from Abstracts
Coffee Break
9:00–9:20 AM
 Van Horne Foyer
Poster Setup
11:00–1:00 PM
 Van Horne C
On Own for Lunch
11:00–5:00 PM
Poster Viewing
1:00–10:00 PM
 Van Horne C
Career Roundtable
3:00–4:30 PM
 Van Horne B
Coffee Available
4:30–5:00 PM
 Van Horne Foyer
Induced Proximity to Modulate Protein Complexes
5:00–7:00 PM
 Van Horne A
Katherine Kayser-Bricker, Halda Therapeutics
Regulated Induced Proximity Targeting Chimeras (RIPTACs)
Michelle R. Arkin, University of California, San Francisco
Utilization of Stabilizers of Protein-Protein Interactions
Jian Jin, Icahn School of Medicine at Mount Sinai
New Approaches to Target Undruggable Proteins
Short Talk(s) Chosen from Abstracts
Asad Taherbhoy, Foghorn Therapeutics
Novel Strategies of Targeting the Transcriptional Machinery for Degradation
Social Hour with Dinner
7:00–8:00 PM
 President's Hall
Posters
7:30–10:00 PM
 Van Horne C
Thursday, February 26, 2026
Breakfast
7:00–8:00 AM
 President's Hall
Clinical Progress in Induced Proximity Approaches
8:00–11:00 AM
 Van Horne A
Neil Bence, Bristol Myers Squibb
BMS Protein Degrader from Discovery to Clinical Development
Paula O’Connor, Nurix Therapeutics
Advancing Novel Degraders to the Clinic (BTK and Beyond)
Michael Feldman, Kymera Therapeutics
KT-621: First STAT6-Targeted Medicine in Clinical Development
Sheryl Gough, Arvinas Inc
The PROTAC Mode of Action Makes Therapeutic Targeting of BCL6 Possible
Short Talk(s) Chosen from Abstracts
Coffee Break
9:00–9:20 AM
 Van Horne Foyer
On Own for Lunch
11:00–5:00 PM
Panel Discussion: Driving Innovation: From Concept to Company, how to Start a Company around a New Idea
2:30–4:30 PM
 Van Horne A
Coffee Available
4:30–5:00 PM
 Van Horne Foyer
Enabling Discovery and Development of Novel Induced Proximity Molecules and Glues
5:00–6:45 PM
 Van Horne A
Georg E. Winter, CeMM Research Center for Molecular Medicine
Novel Glue Discovery via Isogenic Morphological Profiling
Alessio Ciulli, University of Dundee, School of Life Sciences
Expanding the Target Space of Protein Degraders
Lauren V Albrecht, University of California Irvine
MrTAC: Proximity Induced Methylation and Lysosomal Degradation
Short Talk(s) Chosen from Abstracts
Meeting Wrap-Up: Outcomes and Future Directions
6:45–7:00 PM
 Van Horne A
Social Hour with Dinner
7:00–8:00 PM
 President's Hall
Entertainment
8:00–11:00 PM
Cash Bar
8:00–11:00 PM
Friday, February 27, 2026
Departure
12:00–11:59 PM

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