Hematopoiesis
Feb 23–26, 2026 | Keystone Resort, Keystone, CO, United States
Scientific Organizers:
Vijay G. Sankaran, Anna E. Beaudin, and Esther Obeng
In Person
On Demand
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Feb 23–26, 2026 | Keystone Resort, Keystone, CO, United States
Scientific Organizers: Vijay G. Sankaran, Anna E. Beaudin, and Esther Obeng
Vijay G. Sankaran
Boston Children’s Hospital
Vijay G. Sankaran, M.D., Ph.D., is the Jan Ellen Paradise, MD Professor of Pediatrics at Harvard Medical School and Boston Children’s Hospital, an Investigator of the Howard Hughes Medical Institute, an Attending Physician in the Dana-Farber/Boston Children’s Cancer and Blood Disorders Center, and an Associate Member of the Broad Institute. His research focuses on how genetic differences affect blood and immune cell production, leading to new treatments for blood disorders like sickle cell disease and beta-thalassemia. Dr. Sankaran has received several prestigious awards and is a member of the American Society of Clinical Investigation and the Association of American Physicians. Dr. Sankaran actively organizes scientific conferences and collaborations in hematopoiesis research.
Anna E. Beaudin, PhD
University of Utah School of Medicine
Anna Beaudin, Ph.D., is the John W. Athens and Georgia Athens Endowed Chair and Associate Professor and the Associate Chief of Research in the Division of Hematology and Hematologic Malignancies at the University of the Utah School of Medicine/Huntsman Cancer Institute. Dr. Beaudin directs the NIDDK-sponsored Cooperative Center for Excellence in Hematology and the National Central Coordinating Center for the NIDDK Hematology Program. Her lab studies how early life factors affect disease risk by examining fetal blood stem cells. Her research is funded by the NIH, the Pew Biomedical Scholars Award, and the Hellman Fellows Award. Dr. Beaudin is involved in leadership roles in various national and international hematology and immunology societies.
Esther Obeng
St. Jude Children's Research Hospital
Esther Obeng, M.D., Ph.D., is an Assistant Member in the Divisions of Molecular Oncology and Experimental Hematology and an Attending Physician on the Bone Marrow Transplant and Cellular Therapy Service at St. Jude Children’s Research Hospital in Memphis, TN. Dr. Obeng created the first mouse model of the most common gene mutation in myelodysplastic syndrome. Her research focuses on understanding how genetic mutations lead to pre-leukemic conditions and clonal hematopoiesis and is studying the impact of these mutations in pediatric cancer survivors and sickle cell disease patients. Dr. Obeng is an active member of the national hematology community and actively participates in professional societies and conferences; recently serving as Chair of the American Society of Hematology (ASH) Scientific Committee on Myeloid Biology and the Scientific Program Co-Chair for the 2025 ASH Annual Meeting.
Available Formats:
Supported by:
In Person
On Demand
***Meeting program subject to change.
Available Formats: = In Person = On DemandMonday, February 23, 2026
Fundraising
Booking Function
Merchandise Options
Registration Options
Registration
4:00–8:00 PM
Longs Peak Foyer
Welcome Mixer
6:00–8:00 PM
Longs Peak Foyer
Tuesday, February 24, 2026
Breakfast
7:00–8:00 AM
Quandary Peak
Welcome Remarks
8:00–8:10 AM
Grays Peak
Keynote Address
8:10–9:00 AM
Grays Peak
* Anna E. Beaudin, University of Utah School of Medicine
Session Chair
Session Chair
Margaret A Goodell, Baylor College of Medicine
Mosaicism in Hematopoiesis
Mosaicism in Hematopoiesis
Developmental Hematopoiesis
9:00–11:15 AM
Grays Peak
Leonard I. Zon, HHMI/Boston Children's Hospital
Zebrafish Developmental Hematopoiesis
Zebrafish Developmental Hematopoiesis
* Anna E. Beaudin, University of Utah School of Medicine
Developmental Hematopoiesis
Developmental Hematopoiesis
Anne H Carroll, Albert Einstein College of Medicine
Short Talk: Spatiotemporal and Molecular Regulation of Embryonic Lymphoid Progenitor Production
Short Talk: Spatiotemporal and Molecular Regulation of Embryonic Lymphoid Progenitor Production
Stefan Radtke, Fred Hutchinson Cancer Center
Short Talk: CD90 – More Than just a Stem Cell Marker: Implication for Blood Development, Cancer Immunotherapy, and Gene Therapy
Short Talk: CD90 – More Than just a Stem Cell Marker: Implication for Blood Development, Cancer Immunotherapy, and Gene Therapy
Coffee Break
9:30–9:50 AM
Longs Peak Foyer
Award Recipient Acknowledgement
9:50–9:55 AM
Grays Peak
Meet the Editors
11:15–12:15 PM
Grays Peak
Esther Obeng, Emory University School of Medicine
*Session Chair, Blood Editorial Board
*Session Chair, Blood Editorial Board
Gaia Trincucci, Journal of Experimental Medicine
Deputy Editor, JEM
Deputy Editor, JEM
Margaret A Goodell, Baylor College of Medicine
Editorial Board, Cell Stem Cell & Cancer Cell
Editorial Board, Cell Stem Cell & Cancer Cell
Poster Setup
12:15–1:00 PM
Quandary Peak
On Own for Lunch
12:15–2:30 PM
Poster Viewing
1:00–10:00 PM
Quandary Peak
Symposia Spotlight 1
2:30–4:30 PM
Grays Peak
* Esther Obeng, Emory University School of Medicine
Session Chair
Session Chair
Jonathan S. Weissman, Whitehead Institute, HHMI, and MIT
Long Talk: Lineage Tracing of Native Hematopoiesis
Long Talk: Lineage Tracing of Native Hematopoiesis
Cecilia Cotta-Ramusino, Tessera Therapeutics
Long Talk: In Vivo Genome Engineering of HSCs in Sickle Cell Disease
Long Talk: In Vivo Genome Engineering of HSCs in Sickle Cell Disease
Yoon-A Kang, Washington University in St. Louis
Unfolded Protein Response Signaling Promotes Myeloid Cell Production and Cooperates with Oncogenic Mutation
Unfolded Protein Response Signaling Promotes Myeloid Cell Production and Cooperates with Oncogenic Mutation
Alan B. Cantor, Boston Children's Hospital/Dana-Farber Cancer Institute, Harvard Medical School
Megakaryocyte p53 activation in ANKRD26-Related Thrombocytopenia and Leukemia Predisposition
Megakaryocyte p53 activation in ANKRD26-Related Thrombocytopenia and Leukemia Predisposition
Morgan Walcheck, Boston Children's Hospital
Stress-responsive Embryonic HSC Fate is Balanced via the AHR-NLRP3 Inflammasome Axis
Stress-responsive Embryonic HSC Fate is Balanced via the AHR-NLRP3 Inflammasome Axis
Nikita A Vantsev, University of Pennsylvania
PITPβ Drives Jak2V617F-mediated Myeloproliferative Neoplasms in Mice Through AKT Activation
PITPβ Drives Jak2V617F-mediated Myeloproliferative Neoplasms in Mice Through AKT Activation
Coffee Available
4:30–5:00 PM
Longs Peak Foyer
Hematopoietic Stem Cell Biology
5:00–7:00 PM
Grays Peak
* Robert A.J. Signer, University of California, San Diego
HSC Regulation by the Proteostasis Network
HSC Regulation by the Proteostasis Network
Shalin H. Naik, Walter & Eliza Hall Institute
Clonal Dynamics of HSC Contributions to Hematopoiesis
Clonal Dynamics of HSC Contributions to Hematopoiesis
Raffaella Di Micco, Ospedale San Raffaele
Stress Responses in HSCs
Stress Responses in HSCs
Victoria Lawless, Weill Cornell Medicine
Short Talk: An IFN-gamma-Mediated Adaptive Immune Signaling Axis in Bone Marrow Reprograms Hematopoietic Stem Cells to Improve Myeloid Function
Short Talk: An IFN-gamma-Mediated Adaptive Immune Signaling Axis in Bone Marrow Reprograms Hematopoietic Stem Cells to Improve Myeloid Function
Lea Flippe, Murdoch Children's Research Institut
Short Talk: MECOM Expression Tracks Haematopoietic Development from Artery to Engraftable iHSCs
Short Talk: MECOM Expression Tracks Haematopoietic Development from Artery to Engraftable iHSCs
Social Hour with Dinner
7:00–8:00 PM
Quandary Peak
Poster Session 1
7:30–10:00 PM
Quandary Peak
Wednesday, February 25, 2026
Breakfast
7:00–8:00 AM
Quandary Peak
Hematopoietic Microenvironment
8:00–11:00 AM
Grays Peak
* Kellie Machlus, Boston Children's Hospital and Harvard Medical School
Session Chair
Session Chair
Daniel Lucas, Cincinnati Children's Medical Center
Imaging of the Bone Marrow Spatial Architecture
Imaging of the Bone Marrow Spatial Architecture
Louise E Purton, St. Vincent's Institute of Medical Research
Regulation of Hematopoiesis and Bone Marrow Failure Syndromes by Dysregulated Endothelial Cells
Regulation of Hematopoiesis and Bone Marrow Failure Syndromes by Dysregulated Endothelial Cells
Rebekka Schneider, Erasmus MC
MPN Microenvironment
MPN Microenvironment
Sean J. Morrison, University of Texas Southwestern Medical Center
Niche Regulation of HSCs
Niche Regulation of HSCs
Christina M Termini, Fred Hutchinson Cancer Center
Short Talk: Depletion of Microenvironmental Syndecan-2 Impairs Hematopoietic Stem Cell Self-Renewal and Cytokine Responses
Short Talk: Depletion of Microenvironmental Syndecan-2 Impairs Hematopoietic Stem Cell Self-Renewal and Cytokine Responses
Bo Shen, Tsinghua University
Short Talk: Mammalian Bone Marrow Adipocytes Fuel Hematopoietic Maintenance and Regeneration
Short Talk: Mammalian Bone Marrow Adipocytes Fuel Hematopoietic Maintenance and Regeneration
Coffee Break
9:00–9:20 AM
Longs Peak Foyer
Poster Setup
11:00–1:00 PM
Quandary Peak
On Own for Lunch
11:00–5:00 PM
Poster Viewing
1:00–10:00 PM
Quandary Peak
Career Roundtable (Joint)
1:30–2:45 PM
Longs Peak
Lidia Bosurgi, University Medical Center Hamburg-Eppendorf
Group Leader, Professor
Group Leader, Professor
Dale Starkie, DJS Antibodies - AbbVie
Director
Director
Christina M Termini, Fred Hutchinson Cancer Center
Assistant Professor
Assistant Professor
Stella J Berendam, Astrazeneca
Discovery Safety Science Specialist, Immunotoxicology
Discovery Safety Science Specialist, Immunotoxicology
Coffee Available
4:30–5:00 PM
Longs Peak Foyer
Aging, Inflammation, and Disease
5:00–7:00 PM
Grays Peak
* Amelie Collins, Cincinnati Children's Hospital Medical Center
Session Chair
Session Chair
Jennifer Trowbridge, The Jackson Laboratory
Selective Advantage and Selective Vulnerability in Clonal Hematopoiesis
Selective Advantage and Selective Vulnerability in Clonal Hematopoiesis
Luis Batista, Huntsman Cancer Institute, University of Utah
Impaired Post-transcriptional Processing of ncRNAs Trigger Hematopoietic Failure
Impaired Post-transcriptional Processing of ncRNAs Trigger Hematopoietic Failure
Vijay G. Sankaran, Boston Children’s Hospital
Insights from Blood Disorders Enable New Therapies
Insights from Blood Disorders Enable New Therapies
Julia Belk, Stanford
Short Talk: Clonal Hematopoiesis and the Aging Brain
Short Talk: Clonal Hematopoiesis and the Aging Brain
Nader Yatim, Icahn School of Medicine at Mount Sinai
Short Talk: Impaired Polyamine Metabolism Drives Hematopoietic Aging
Short Talk: Impaired Polyamine Metabolism Drives Hematopoietic Aging
Social Hour with Dinner
7:00–8:00 PM
Quandary Peak
Poster Session 2
7:30–10:00 PM
Quandary Peak
Thursday, February 26, 2026
Breakfast
7:00–8:00 AM
Quandary Peak
Cutting Edge Innovations in Hematopoiesis
8:00–11:00 AM
Grays Peak
* Weike Pei, Westlake University
Session Chair
Session Chair
Vanessa M Scanlon, UConn Health
Remote Presentation: Consequences of Erythropoietin Signaling in Megakaryocytic-Erythroid Progenitors
Remote Presentation: Consequences of Erythropoietin Signaling in Megakaryocytic-Erythroid Progenitors
Britta Will, Albert Einstein College of Medicine
Metabolic Regulation of HSCs
Metabolic Regulation of HSCs
Sara Tomei, Walter and Eliza Institute Hall of Medical Research
Short Talk: Clonal Multi-omics Uncovers CD200 as a Marker for Bona Fide HSCs
Short Talk: Clonal Multi-omics Uncovers CD200 as a Marker for Bona Fide HSCs
Anna-Lena Neehus, Boston Children's Hospital
Short Talk: Stalled B Cell Development as a Convergent Mechanism for Germline Predisposition to Childhood Leukemia
Short Talk: Stalled B Cell Development as a Convergent Mechanism for Germline Predisposition to Childhood Leukemia
Arushana A Maknojia, Baylor College of Medicine
Short Talk: An Unusual Friendship: How Gut Microbiota and Endogenous Retroviruses (ERVs) Interact to Support Hematopoiesis?
Short Talk: An Unusual Friendship: How Gut Microbiota and Endogenous Retroviruses (ERVs) Interact to Support Hematopoiesis?
Amanda J Daniels, University of California - San Diego
Short Talk: Enhancing Translation Fidelity Confers Hematopoietic Stem Cells with Increased Resistance to Stress and Suppresses Cancer Initiation
Short Talk: Enhancing Translation Fidelity Confers Hematopoietic Stem Cells with Increased Resistance to Stress and Suppresses Cancer Initiation
Peter Kurre, University of Pennsylvania
Short Talk: MYC as a Central Player in Fanconi Anemia Associated Hematopoiesis Failure
Short Talk: MYC as a Central Player in Fanconi Anemia Associated Hematopoiesis Failure
Teng Gao, Boston Children's Hospital
Short Talk: Robust Single-Cell Multiomic Lineage Tracing of Human Hematopoiesis Enabled by Population-Genetic Modeling of Mitochondrial DNA Drift
Short Talk: Robust Single-Cell Multiomic Lineage Tracing of Human Hematopoiesis Enabled by Population-Genetic Modeling of Mitochondrial DNA Drift
Coffee Break
9:00–9:20 AM
Longs Peak Foyer
On Own for Lunch
11:00–5:00 PM
Symposia Spotlight 2
2:30–4:30 PM
Grays Peak
* Jennifer Trowbridge, The Jackson Laboratory
Session Chair
Session Chair
Bianca E Bean, University of Florida
Netrin-1 Regulates Hematopoietic Stem Cell Function via UNC5A
Netrin-1 Regulates Hematopoietic Stem Cell Function via UNC5A
Michalis Agathocleous, University of Texas Southwestern Medical Center
Stem Cell Function and Hematopoiesis in the Absence of Carbohydrate Oxidation and Fermentation
Stem Cell Function and Hematopoiesis in the Absence of Carbohydrate Oxidation and Fermentation
Shinya Fujita, National Institute of Global Health and Medicine, Japan Institute for Health Security
Piezo1 Mechanosensing as a Druggable Target to Enhance Hematopoietic Stem Cell Homing to Bone Marrow
Piezo1 Mechanosensing as a Druggable Target to Enhance Hematopoietic Stem Cell Homing to Bone Marrow
Chia-Jo Chen, Cincinnati Children's Hospital Medical Center
Asynchronous Acquisition of Hematopoietic Stem Cell Functional Maturity During Postnatal Development
Asynchronous Acquisition of Hematopoietic Stem Cell Functional Maturity During Postnatal Development
Sulagna Sanyal, University of Pennsylvania
YY1 Depletion Reprograms Committed Murine Pro-B Cells to Acquire Hematopoietic Stem Cell Properties
YY1 Depletion Reprograms Committed Murine Pro-B Cells to Acquire Hematopoietic Stem Cell Properties
Jill Henrich, University of Pennsylvania
Regulation of Ribosomal RNA Transcription by MYC in Hematopoiesis
Regulation of Ribosomal RNA Transcription by MYC in Hematopoiesis
James Swann, Columbia University
Molecular Cartography of Emergency Myelopoiesis Reveals Conserved Modules of Hematopoietic Activation in Inflammation and Leukemia
Molecular Cartography of Emergency Myelopoiesis Reveals Conserved Modules of Hematopoietic Activation in Inflammation and Leukemia
Coffee Available
4:30–5:00 PM
Longs Peak Foyer
Hematologic Malignancies
5:00–6:45 PM
Grays Peak
* Michael G Kharas, Memorial Sloan Kettering Cancer Center
Session Chair
Session Chair
Catriona H.M. Jamieson, University of California, San Diego
Myeloid Malignancies
Myeloid Malignancies
Esther Obeng, Emory University School of Medicine
Pathogenesis of MDS
Pathogenesis of MDS
John E. Dick, Princess Margaret Cancer Centre
What Makes a Stem Cell a Stem Cell and How Does It Go Bad
What Makes a Stem Cell a Stem Cell and How Does It Go Bad
Yuanyuan Wang, UCLA
Short Talk: Unraveling Stemness Mechanisms in MECOM Rearranged Acute Myeloid Leukemias
Short Talk: Unraveling Stemness Mechanisms in MECOM Rearranged Acute Myeloid Leukemias
Meeting Wrap-Up: Outcomes and Future Directions (Organizers)
6:45–7:00 PM
Grays Peak
Social Hour with Dinner
7:00–8:00 PM
Quandary Peak
Cash Bar
8:00–9:00 PM
Quandary Peak
Entertainment
8:00–9:00 PM
Quandary Peak
Friday, February 27, 2026
Departure
12:00–11:59 PM
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