Joint with: Computational Drug Discovery: Tools Across the Translational Pipeline
Antibodies as Drugs: Evolving Designs, Formats and Approaches

Feb 22–25, 2027 | Fairmont Banff Springs, Banff, AB, Canada
Scientific Organizers: James E Crowe, Jr., Lisa Purcell, and Jonah Rainey

  In Person
  On Demand
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Feb 22–25, 2027 | Fairmont Banff Springs, Banff, AB, Canada

Scientific Organizers: James E Crowe, Jr., Lisa Purcell, and Jonah Rainey

Supported by the  Directors' Fund

***Meeting program subject to change.

Available Formats:   = In Person     = On Demand
Monday, February 22, 2027
Registration
4:00–8:00 PM
Welcome Mixer
6:00–8:00 PM
Tuesday, February 23, 2027
Breakfast
7:00–8:00 AM
Welcome and Keynote Address (Joint)
8:00–9:00 AM
James Zou, Stanford University
The Virtual Lab
Drug Design and Preclinical Development: Stimulating Therapeutics and Translation (Joint)
9:00–11:15 AM
Dean Ho, National University of Singapore
Simulating First-in-Human Dosing Studies in Oncology
Speaker to be Announced
Philip Kim, University of Toronto
Computation and Artificial Intelligence-Based Methods for Better Antibody Development
Mohamed Shahin †, Pfizer
Modeling and Simulations Meet AI for Clinical Pharmacology
Short Talk(s) Chosen from Abstracts
Coffee Break
9:30–9:50 AM
Poster Setup
11:15–1:00 PM
On Own for Lunch
11:15–5:00 PM
Poster Viewing
1:00–10:00 PM
Symposia Spotlight 1: Late-breaking research presentations selected from abstract submissions
2:30–4:30 PM
Short Talks Chosen from Abstracts
Coffee Available
4:30–5:00 PM
Bispecific Antibodies for Co-Engagement and Co-Stimulation
5:00–7:00 PM
Shelley Force Aldred, Rondo Therapeutics
Co-Stimulatory Bispecifics
Koorosh Korfi †, Roche
CD28 and 4-1BB Costimulation in Combination Therapies
Short Talk(s) Chosen from Abstracts
Social Hour with Dinner
7:00–8:00 PM
Posters
7:30–10:00 PM
Wednesday, February 24, 2027
Breakfast
7:00–8:00 AM
New Dosing and Use Paradigms for Multispecific Antibodies
8:00–11:00 AM
Paul W. H. I. Parren, Leiden University Medical Center
Deep-Depletion of Tissue-Resident Pathogenic Immune Cells
Nina Weisser, Zymeworks BC Inc.
TriTCE Co-stim: A Differentiated T Cell Engager Platform with Conditional cis CD28 Co-Stimulation and Transferability to Diverse Targeting Strategies
Peyton Greenside †, BigHat Biosciences
TCE for Diverse Targets
Jonah Rainey, Lilly
Talk Title to be Announced
Short Talk(s) Chosen from Abstracts
Coffee Break
9:00–9:20 AM
Poster Setup
11:00–1:00 PM
On Own for Lunch
11:00–5:00 PM
Poster Viewing
1:00–10:00 PM
Career Roundtable
3:00–4:30 PM
Coffee Available
4:30–5:00 PM
Conditionally and Selectively Active Antibodies
5:00–6:30 PM
Meike Logtenberg †, Merida Biosciences
Selective Binding and Clearance of Pathogenic Antibodies
Cathy Chang †, BioAlta, LLC.
Protein-Associated Chemical Switches for Conditionally Active Biologics
Short Talk(s) Chosen from Abstracts
Panel Discussion 1: The Cutting-Edge of Antibody Engagement
6:30–7:00 PM
Social Hour with Dinner
7:00–8:00 PM
Posters
7:30–10:00 PM
Thursday, February 25, 2027
Breakfast
7:00–8:00 AM
Application of Innovations to Exogenous Antibody Targets to Expand Breadth and Efficacy
8:00–11:00 AM
David Veesler, University of Washington
Antibody Inhibition of Activation Mechanisms of Coronavirus Spike
Laura M Walker, Moderna
Alternative Expression of Antibodies
James E Crowe, Jr., Vanderbilt University Medical Center
Human Monoclonal Antibodies for Emerging Infectious Diseases
Lisa Purcell, Third Rock Ventures
Novel Structure-Guided Functional Improvement of Antibody Breadth and Potency
Short Talk(s) Chosen from Abstracts
Coffee Break
9:00–9:20 AM
On Own for Lunch
11:00–5:00 PM
Symposia Spotlight 2: Late-breaking research presentations selected from abstract submissions
2:30–4:30 PM
Short Talks Chosen from Abstracts
Coffee Available
4:30–5:00 PM
Novel Scaffolds and Immunoconjugates
5:00–6:30 PM
Bradley Pentelute †, Massachusetts Institute of Technology
Efficient Drug Delivery through Selective Modification of Proteins
Pawel Stocki †, Ossianix
Brain Shuttles for Targeted Delivery
Jason Laliberte, AstraZeneca
VHH-Based Antibodies for Broad Influenza Targeting
Short Talk(s) Chosen from Abstracts
Panel Discussion 2: How Far Is Too Far: Target Engagement, Computational Design and New Scaffolds
6:30–7:00 PM
Meeting Wrap-Up: Outcomes and Future Directions (Organizers)
6:45–7:00 PM
Social Hour with Dinner
7:00–8:00 PM
Entertainment
8:00–11:00 PM
Cash Bar
8:00–11:00 PM
Friday, February 26, 2027
Departure
12:00–11:59 PM

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