Joint with: Neurodegeneration: From Mechanisms to Precision Diagnosis and Therapies
Neural-Immune Interactions: Immune Modulation of CNS Biology

Apr 11–14, 2027 | Whistler Conference Centre, Whistler, BC, Canada
Scientific Organizers: Dimitry Ofengeim, Martin Kerschensteiner, and Soyon Hong

  In Person
  On Demand
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Apr 11–14, 2027 | Whistler Conference Centre, Whistler, BC, Canada

Scientific Organizers: Dimitry Ofengeim, Martin Kerschensteiner, and Soyon Hong

Supported by the  Directors' Fund

***Meeting program subject to change.

Available Formats:   = In Person     = On Demand
Sunday, April 11, 2027
Registration
4:00–8:00 PM
Welcome Mixer
6:00–8:00 PM
Monday, April 12, 2027
Breakfast
7:00–8:00 AM
Welcome and Keynote Session (Joint)
8:00–9:30 AM
Alfred Njamnshi †, University of Yaoundé
Infectious Disease Life-Time Impact on Cognition
Daniel S. Reich †, NINDS, National Institutes of Health
Combining Advanced Imaging and Biological Insights for Better Disease Progression
Coffee Break
9:30–9:50 AM
Molecular Insights into the Interplay between Neurodegeneration and Neuroinflammation (Joint)
9:30–11:15 AM
Li Gan †, Weill Cornell Medicine
Converging Molecular Mechanisms of Neurodegeneration
Mariko Bennett †, University of Pennsylvania
The Potential of Microglia-Based Therapies in Neurodegeneration
David M Holtzman †, Washington University
Innate and Adaptive Immune System in tau-Mediated Neurodegeneration
Short Talk(s) Chosen from Abstracts
Panel Discussion 1: New Modalities in Neuro-Diagnosis and Therapeutics (Joint)
11:15–12:15 PM
Poster Setup
12:15–1:00 PM
On Own for Lunch
12:15–5:00 PM
Poster Viewing
1:00–10:00 PM
Symposia Spotlight 1: Late-breaking research presentations selected from abstract submissions
2:30–4:30 PM
Short Talks Chosen from Abstracts
Coffee Available
4:30–5:00 PM
Glial and Innate Drivers of CNS Inflammation
5:00–7:00 PM
Brad Zuchero †, Stanford University
Oligodendrocytes Plasticity and Immune Drivers
Soyon Hong, University College London
Microglia-Synapse Biology in Brain Homeostasis and Pathology
Martin Kerschensteiner, Ludwig Maximilians University Munich
Myeloid Cell Actions and Interactions in the Inflamed CNS
Short Talk(s) Chosen from Abstracts
Social Hour with Dinner
7:00–8:00 PM
Posters
7:30–10:00 PM
Tuesday, April 13, 2027
Breakfast
7:00–8:00 AM
The Role of the Adaptive Immune System Beyond Autoimmunity
8:00–11:00 AM
Menna R Clatworthy †, University of Cambridge
Immune Cells in Border Tissues Protect the CNS from Infection and Contribute to CNS Diseases
Arthur Liesz †, Ludwig-Maximilians-Universität München
Deleterious and Beneficial Roles of the Adaptive Immune System following Brain Ischemia
Doron Merkler †, University of Geneva
Role of Tissue Resident T cells in CNS Infection and Immunity
Dimitry Ofengeim, Sanofi
Interplay of the Innate and Adaptive Immune System in Neurodegeneration
Short Talk(s) Chosen from Abstracts
Coffee Break
9:00–9:20 AM
Panel Discussion 2: Different Perspectives on the Emerging Challenges/Opportunities for Research and Therapy in Neuroimmunology
11:00–12:00 PM
Poster Setup
11:00–1:00 PM
On Own for Lunch
11:00–5:00 PM
Poster Viewing
1:00–10:00 PM
Career Roundtable
3:00–4:30 PM
Coffee Available
4:30–5:00 PM
Emerging Concepts of Neuro-Immune Communication
5:00–7:00 PM
Michael T Heneka †, University of Luxembourg
Structural and Molecular Bridges between Neurons and Microglia
Gloria Choi †, Massachusetts Institute of Technology
Cytokines as Modulators of Neuronal Activity and Development
Isaac Chiu †, Harvard Medical School
Neuronal Pathogen Sensing Mechanism in Neuroinflammation and Neurodegeneration
Short Talk(s) Chosen from Abstracts
Social Hour with Dinner
7:00–8:00 PM
Posters
7:30–10:00 PM
Wednesday, April 14, 2027
Breakfast
7:00–8:00 AM
Translating Innovation: Clinical Advances in Neurodegeneration and Neuroimmunology (Joint)
8:00–11:00 AM
Henrik Zetterberg †, University of Gothenburg
Biomarkers in Neurodegeneration and Neuroinflammation
Manuela Polydoro †, Muna Therapeutics
Translational Biomarkers in Drug Discovery
James Keaney †, F. Hoffmann-La Roche
Omics Approaches to Drug Discovery in Neurodegeneration and Neuroinflammation
Joy Yu Zuchero †, Denali Therapeutics Inc
Challenges for CNS Drug-Discovery
Short Talk(s) Chosen from Abstracts
Coffee Break
9:00–9:20 AM
Workshop: How we can Work Together to Strengthen our Scientific Integrity and Communication with Public and also the Current Naysayers about Translational Avenues in Neurodegeneration
11:00–12:00 PM
On Own for Lunch
12:00–5:00 PM
Symposia Spotlight 2: Late-breaking research presentations selected from abstract submissions
2:30–4:30 PM
Short Talks Chosen from Abstracts
Coffee Available
4:30–5:00 PM
Regulation of Immune Responses across Compartments
5:00–6:45 PM
Andrew Yang †, University of California, San Francisco
Decoding Immune and Protein Crosstalk between the Brain and Body
Rejane Rua †, CIML
Exploring the Functions of the Immune Sentinels at the Brain Borders to Control Neuroinflammation
Maria Lehtinen †, Harvard Medical School
The Choroid Plexus: A Command Center for Brain-Body Communication during Inflammation
Short Talk(s) Chosen from Abstracts
Meeting Wrap-Up: Outcomes and Future Directions (Organizers)
6:45–7:00 PM
Social Hour with Dinner
7:00–8:00 PM
Cash Bar
8:00–11:00 PM
Entertainment
8:00–11:00 PM
Thursday, April 15, 2027
Departure
12:00–11:59 PM

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