Cardiovascular Epigenetics and Gene Regulation

Apr 15–18, 2024 | Herrenhausen Palace, Hannover, Germany
Scientific Organizers: Roger Foo, Federica Accornero, and Enzo R. Porrello

  In Person
  On Demand
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Apr 15–18, 2024 | Herrenhausen Palace, Hannover, Germany

Scientific Organizers: Roger Foo, Federica Accornero, and Enzo R. Porrello

Supported by the  Directors' Fund

***Meeting program subject to change.

Available Formats:   = In Person     = On Demand
Monday, April 15, 2024
Arrival and Registration  
4:00–8:00 PM
 Grand Mussmann Hotel, Tivoli Room
Welcome Mixer  
6:00–8:00 PM
 Central-Hotel Kaiserhof
Tuesday, April 16, 2024
Breakfast  
8:00–9:00 AM
 Individual Hotel
Poster Setup  
8:30–9:00 AM
 Ballroom
Welcome and Keynote Address  
9:00–10:00 AM
 Auditorium
Wolf Reik, Altos Labs, Cambridge Institute of Science
Epigenetic Reprogramming in Development and Ageing
Poster Viewing  
9:00–7:00 PM
 Ballroom
Epigenome, 3D Chromatin Conformation and New Technology  
10:00–12:15 PM
 Auditorium
Leslie A. Leinwand, University of Colorado Boulder
Plasticity in the Heart in Health and Disease
Yibin Wang, Duke-NUS, Singapore
Ribosome Biogenesis Control in Cardiac Hypertrophy
Emily S. Wong, Victor Chang Cardiac Research Institute
Evolutionary Enhancer Code and 3D Chromatin
Lorenz H Lehmann, University of Heidelberg
Short Talk: Short Talk: A Memorized Superenhancer Regulates Metabolic Flexibility via Retinoid Acid Signaling in the Heart
Coffee Break  
10:30–10:50 AM
 Foyer
Lunch  
12:15–1:15 PM
 Ballroom
Poster Session  
1:00–3:00 PM
 Ballroom
Career Roundtable  
3:30–4:30 PM
 Ballroom
Yibin Wang, Duke-NUS, Singapore
Professor & Director
Gergana Dobreva, Heidelberg University
Professor & Medical Faculty
Xuhui Feng, Bristol Myers Squibb
Senior Scientist
Coffee Available  
4:30–5:00 PM
 Foyer
Gene Regulation, Cell States and Regeneration  
5:00–7:00 PM
 Auditorium
Enzo R. Porrello, Murdoch Children's Research Institute
Enhancing Maturation of Stem Cell-derived Cardiomyocytes
Li Qian, University of North Carolina at Chapel Hill
Epigenetic Regulation of Cardiac Reprogramming
Lynn Devilee, QIMR Berghofer
Short Talk: Short Talk: Cell Cycle Re-Entry Follows Functional Inhibition of Cardiomyocytes in Mature Human Cardiac Organoids
Ahmed I. Mahmoud, University of Wisconsin - Madison
Short Talk: Short Talk: Decoding the Interplay Between Metabolism and Epigenetics During Adult Heart Regeneration
Nathan Palpant, University of Queensland
Short Talk: HOPX Associated Molecular Programs Control Cardiomyocyte Cell States Underpinning Cardiac Development and Disease
Shambhabi Chatterjee, Hannover Medical School
Short Talk: Short Talk: Telomerase is Crucial for Survival, Function and Regeneration of Cardiomyocytes
Social Hour with Lite Bites  
7:00–8:00 PM
 Ballroom
Wednesday, April 17, 2024
Breakfast  
8:00–9:00 AM
 Individual Hotel
Metabolism, Obesity and Gene Regulation  
9:00–12:00 PM
 Auditorium
Thomas Thum, Medical School Hannover
Preclinical and Clinical Development of Noncoding RNA Therapeutics for Cardiovascular Diseases
Johannes Backs, University of Heidelberg
HDAC Signaling in Cardiometabolic Disease
Kathy Lui, Chinese University of Hong Kong
YY1 Epigenetically Orchestrates Vascular Contraction by Controlling transcript Stability in VSMCs
Pieterjan Dierickx, Max Planck for Heart & Lung Research
Short Talk: Short Talk: NAD+ Controls Circadian Rhythmic Gene Expression During Cardiac Aging
Niranjana Natarajan, Universitty of Pittsburgh
Short Talk: Short Talk: Epigenetic Regulation of Macrophage Function in Cardiovascular Disease
Emmanouil Georgios Solomonidis, Goethe University
Short Talk: Short Talk: Hematopoietic Loss of KDM6A Impairs Cardiac Recovery Post Myocardial Infarction via Pro-Inflammatory Myeloid Cells
Junedh Mahesh Amrute, Washington University School of Medicine in St. Louis
Short Talk: Short Talk: Runx1 Gene Regulatory Network in Macrophages Facilitates Cardiac Recovery
Coffee Break  
10:00–10:20 AM
 Foyer
Lunch  
12:00–1:00 PM
 Ballroom
Independent Exploration of the Gardens  
1:00–2:30 PM
 Herrenhausen Palace
Workshop  
2:30–4:30 PM
 Auditorium
Alessia Costa, MHH
An Engineered Reporter Tool to Track Human Cardiomyocyte Proliferation
Diana Harleidy Vargas-Trujillo, ALPINA
Effect of Nutritional Modulation in Microbial-Derived Succinate Pathways and its Epigenetic Implications in Cardiovascular Disease
Cheng-Fu Kao, Academia Sinica
Epigenetic Regulator RNF20 Underlies Temporal Hierarchy of Gene Expression to Regulate Postnatal Cardiomyocyte Polarization
Christian Bär, Institute of Molecular and Translational Therapeutic Strategies - IMTTS
Long Non-Coding RNA Foxo6os Prevents Cardiomyocyte Death and Attenuates Myocardial Infarction Injury
Alexandre R. Colas, Sanford-Burnham Medical Research Institute
Transcription Factor-Mediated Control of Chromatin Accessibility During Cardiac Reprogramming
Coffee Available  
4:30–5:00 PM
 Foyer
Histones and DNA Regulatory Elements  
5:00–7:00 PM
 Auditorium
James E. Hudson, QIMR Berghofer Medical Research Institute
BET Inhibitors for CVD
Timothy A. McKinsey, University of Colorado Denver
Unexpected Roles for HDAC11
Roger Foo, National University of Singapore
Multiplex Assessment of Cardiac Distal Regulatory Elements
Artemy Zhigulev, KTH Royal Institute of Technology
Short Talk: Short Talk: The Role of Rare Enhancer Variants in Bicuspid Aortic Valve Pathology
Chang Jie Mick Lee, National University of Singapore
Short Talk: Short Talk: Validating Functional Histone-acetylated Variant Enhancers in Human Hearts using a STARR-seq Approach
Social Hour with Lite Bites  
7:00–8:00 PM
 Ballroom
Thursday, April 18, 2024
Breakfast  
8:00–9:00 AM
 Individual Hotel
Vascular Gene Regulation  
9:00–12:00 PM
 Auditorium
Saptarsi M. Haldar, Amgen Inc.
Drug Discovery in CVD Epigenetics
Costanza Emanueli, Imperial College London
Regulation of MicroRNA Expression and Function in the Human Heart
Hanjoong Jo, Emory University
Flow-induced Vascular Cell Reprogramming and Atherosclerosis by Transcriptomic and Epigenomic Regulation
Gergana Dobreva, Heidelberg University
Epigenetic Regulation of Cardiovascular Cell Fate and Function
Janice Reid, QIMR Berghofer Medical Research Institute
Short Talk: Short Talk: Constructing a Ligand Signaling Transcriptome Encyclopedia for the Heart
Coffee Break  
10:00–10:20 AM
 Foyer
Lunch  
12:00–1:00 PM
 Ballroom
Epitranscriptomics, RNA and DNA Modifications  
1:00–2:45 PM
 Auditorium
Federica Accornero, Brown University
RNA-Dependent Mechanisms of Heart Failure
Ralf Gilsbach, Institute of Experimental Cardiology Heidelberg University Hospital
Decoding and Functional Modulation of Cardiac Regulatory Elements
Izhak Kehat, Technion –Israel Institute of Technology
Localised Translation in Cardiomyocytes
Changcheng Zhou, University of California, Riverside
Short Talk: Short Talk: Paternal Hypercholesterolemia Alters Sperm tsRNAs/rsRNAs and Elicits Sex-Specific Exacerbation of Atherosclerosis in Offspring
Meeting Wrap-Up: Outcomes and Future Directions (Organizers)  
2:45–3:00 PM
 Auditorium
Cocktail Hour with Snacks  
3:00–4:00 PM
 Foyer
Friday, April 19, 2024
Departure  
7:00–11:59 PM

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