Chronic Kidney Disease: Emerging Mechanisms, Consequences and Targeted Treatments

Apr 12–15, 2026 | Fairmont Hotel Vancouver, Vancouver, BC, Canada
Scientific Organizers: Matthias Kretzler, Hiddo Lambers Heerspink, Olga G. Troyanskaya, and Maria Chiara Magnone

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  In Person
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Apr 12–15, 2026 | Fairmont Hotel Vancouver, Vancouver, BC, Canada

Scientific Organizers: Matthias Kretzler, Hiddo Lambers Heerspink, Olga G. Troyanskaya, and Maria Chiara Magnone

Supported by:

***Meeting program subject to change.

Available Formats:     = Livestream   = In Person     = On Demand
Sunday, April 12, 2026
Registration
4:00–8:00 PM
 British/Columbia Foyer
Welcome Mixer Sponsored by Lilly
6:00–8:00 PM
 British/Columbia Foyer
Monday, April 13, 2026
Breakfast
7:30–8:30 AM
 British/Columbia Ballrooms
Welcome Remarks
8:30–8:40 AM
 British Ballroom
Keynote Address
8:40–9:30 AM
 British Ballroom
Gregory Germino, NIH
Advancing a National Vision for Chronic Kidney Disease- from Community to Precision Therapies
CKD Function and Failure; From Models to Man
9:30–11:45 AM
 British Ballroom
Melissa Hallow, University of Georgia
Modelling Kidney Function: What Renal Physiology Teaches us in 2025 for CKD: Lessons Learned from Modeling Endothelin Function in CKD Trials
Samira Musah, Duke University
Kidney Tissue Bioengineering for Patient Level Precision Medicine
Jonathan Himmelfarb, Mount Sinai School of Medicine
Ex vivo Organ Cross Talk: Liver-Kidney System Defines Molecular Cross Talk in Toxin Induced CKD
Annie Moisan †, Roche Pharmaceuticals
Short Talk: A Human-Centric DKD Discovery Pipeline: Integrating Patient Multi-OMICS with Organoid-Derived Models to Identify Novel Renal Cytoprotectants
Coffee Break
10:00–10:20 AM
 British/Columbia Foyer
Poster Setup
11:45–1:00 PM
 Vancouver Island Room
On Own for Lunch
11:45–5:00 PM
Poster Viewing
1:00–10:00 PM
 Vancouver Island Room
Symposia Spotlight
2:30–4:30 PM
 British Ballroom
Kyung Lee, Icahn School of Medicine at Mount Sinai
The Liver as a Silent Driver of CKD: From MASH to Kidney Cell Injury
Robert R Graham, Maze Therapeutics
Expanding the Universe of SLC6A19 Substrates: SLC Inhibition Protects Kidney from Nephrotoxic Metabolite Accumulation
Bernhard Dumoulin, University of Pennsylvania
Spatial Human Kidney Map Highlights B cell driven Kidney Disease Subgroup
Jeong Ho Joo †, Korea Advanced Institute of Science and Technology
Unbiased Transcriptomic Clustering Identifies a STAT1-Driven Inflammatory PEC Endotype at the Glomerular Vascular Pole
Erik Moedt, UMCG
Novel Biomarkers to Monitor Disease Progression and Treatment Response in Patients with CKD and Normoalbuminuria
Alfin Mohammad Abdillah, Chungnam National University
Multi-Omics Dissection of Immune and Epithelial Reprogramming by Small-Molecule CGP-60474 in a Male Murine Model of Adenine-Induced Chronic Kidney Disease
Farsad Afshinnia, University of Michigan
Heart Failure Specific Plasma Acylcarnitine Alterations in Chronic Kidney Disease
Coffee Available
4:30–5:00 PM
 British/Columbia Foyer
Unraveling the Molecular Machinery of the Nephron in Function and Failure
5:00–7:00 PM
 British Ballroom
Laura Barisoni, Duke University
Tissue is the Issue: AI Driven Image Analysis Maps Structural and Molecular Disease Trajectories
Katalin Susztak, University of Pennsylvania
From Mapping to Mechanism to Medicine
Olga G. Troyanskaya, Princeton University
Genes and Environment Driving CKD: Linking Environmental Exposures with Genetic Risk Assessment to Guide CKD Management
Christine Limonte, University of Washington
Short Talk: Redefining Kidney Disease – Clinico-pathological and Molecular Findings from the Kidney Precision Medicine Project 
Insa Schmidt, Boston University
Short Talk: Self-Supervised Learning Identifies Prognostic Tissue Patterns in Chronic Kidney Disease Linked to Molecular Signatures
Social Hour with Dinner
7:00–8:00 PM
 British/Columbia Ballrooms
Poster Session 1
7:30–10:00 PM
 Vancouver Island Room
Tuesday, April 14, 2026
Breakfast
7:30–8:30 AM
 British/Columbia Ballrooms
Poster Setup
8:00–8:30 AM
 Vancouver Island Room
Poster Viewing
8:15–5:00 PM
 Vancouver Island Room
CKD in Obesity and Diabetes: Driving the Disease Burden in the Cardio Metabolic Pandemic
8:30–11:30 AM
 British Ballroom
Tamer Coskun, Eli Lilly & Company
Obesity Driven Metabolic Reprogramming: From Metabolic Profiling to Drug Targets for Cardiorenal Disease
Petter Bjornstad, University of Washington
A Holistic View How Obesity and Diabetes Driving Kidney Disease in Children and Adolescents
Katherine R. Tuttle, University of Washington
Finally Breaking the Death Spiral of CKD: Mechanistic Trials Defining the Mode of Action of the Incretin System
Arianne van Koppen, TNO
Short Talk: Mechanisms, Modulation and Medication Efficacy in a Multifactorial Cardiovascular-Kidney-Metabolic Syndrome Mouse Model with Chronic Kidney Disease and HFpEF
Jennifer Schaub, University of Michigan
Short Talk: HIF Regulatory Network Reflects Kidney Disease Progression in Diabetes and Reversal with SGLT2 Inhibition
Aleksandra Kukla, Mayo Clinic
Short Talk: Inflammatory and Morphologic Characteristics of Perirenal Adipose Tissue in Living Kidney Donors with Obesity: A Prospective Cohort Study
Yukihiro Imakiire †, Chiba University
Short Talk: The Prediction of Renal Decline Reflecting Heterogeneous Aggravation of Diabetic Kidney Disease
Coffee Break
9:30–9:50 AM
 British/Columbia Foyer
Award Recipient Acknowledgement
9:50–9:55 AM
 British Ballroom
Lunch
11:30–12:30 PM
 British/Columbia Ballrooms
Poster Session 2
12:00–2:30 PM
 Vancouver Island Room
Career Roundtable (Joint)
3:00–4:30 PM
 British Ballroom
Coffee Available
4:30–5:00 PM
 British/Columbia Foyer
Primary Glomerular Diseases Driving CKD: Insight into a Rapidly Evolving Targeted Therapy Landscape
5:00–7:00 PM
 British Ballroom
Katherine Bull, University of Oxford
Defining Disease Neighborhoods in Autoimmune Glomerular Diseases
Brad H Rovin, Ohio State University College of Medicine
Innate Immunity Modulation in Lupus Nephritis, Bringing Insight from Trials Back to the Bench
Chee Kay Cheung, University of Leicester
The Right Drug for the Right IgAN in 2025: Impact of Endothelin Blockade on Glomerular Manifestations of IgA Nephritis
Tobias B Huber, University Medical Center Hamburg-Eppendorf
Understanding Filtration Barrier Failure Drives Novel Treatments in Nephrotic Syndrome
On Own for Dinner
7:00–8:00 PM
Wednesday, April 15, 2026
Breakfast
7:30–8:30 AM
 British/Columbia Ballrooms
Genes and Kidney; Unique Opportunities for Targeted Therapies, Lessons Learned from ApoL1 and Beyond
8:30–11:30 AM
 British Ballroom
Whitney Besse, Yale School of Medicine
Polycystic Kidney Disease: The Journey from Gene to Therapies
Martin Pollak, Beth Israel Deaconess Medical Center
ApoL1 Biology and Kidney Disease
Akinlolu Ojo, University of Kansa
ApoL1 across Continents: Lessons Learned on Gene Environment Interaction in H3 Africa KDRN
Glenn Chertow, Stanford University
Lessons Learned from the First Trials Targeting ApoL1 Kidney Disease
Lili Liu †, University of Michigan
Short Talk: Atlas of Glomerular Disease-specific Genetic Effects on Gene Regulation in Blood Empowers New Gene Discovery Studies
Peter Czarnecki, Beth Israel Deaconess Medical Center
Short Talk: Truncating Mutations in BICC1 Cause Autosomal Dominant Tubulointerstitial Kidney Disease
Coffee Break
9:30–9:50 AM
 British/Columbia Foyer
On Own for Lunch
11:30–5:00 PM
Panel: Perspectives: Personalized Medicine and Patient-Centered Strategies (joint)
1:00–2:00 PM
 British Ballroom
Coffee Available
4:30–5:00 PM
 British/Columbia Foyer
Precision Clinical Trial Strategies for Kidney Disease
5:00–6:45 PM
 British Ballroom
Matthias Kretzler, University of Michigan
Lessons Learned from Matching Patients Renal Pathobiology to Targeted Therapies in Glomerular Disease
Maria Chiara Magnone, Abiologics, Inc
Precision Medicine in CKD - A Therapeutic Modality Angle
Hiddo Lambers Heerspink, University Medical Center Groningen
Precision Medicine Trials in CKD: Bringing Molecular Understanding of CKD Drugs to Clinical Care
Anil Karihaloo, Novo Nordisk A/S
Short Talk: From Genetics to Functional Validation: Identification of Putative Novel Genes Implicated in Pathogenesis of Chronic Kidney Disease
Meeting Wrap-Up: Outcomes and Future Directions (Organizers)
6:45–7:00 PM
 British Ballroom
Social Hour with Dinner
7:00–8:00 PM
 British/Columbia Ballrooms
Entertainment
8:00–9:00 PM
 Columbia Ballroom
Thursday, April 16, 2026
Departure
12:00–11:59 PM

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