Hormonal Influences on Immunity and Cancer Across the Lifespan

Jan 01–04, 2027 | Location to be Determined
Scientific Organizers: Suzanne D. Conzen, Amy Moran, and James V. DeGregori

  In Person
  On Demand
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Jan 01–04, 2027 | Location to be Determined

Scientific Organizers: Suzanne D. Conzen, Amy Moran, and James V. DeGregori

Supported by the  Directors' Fund

***Meeting program subject to change.

Available Formats:   = In Person     = On Demand
Friday, January 1, 2027
Registration
4:00–8:00 PM
Welcome Mixer
6:00–8:00 PM
Saturday, January 2, 2027
Breakfast
7:00–8:00 AM
Welcome and Keynote Address
8:00–9:00 AM
Alberto Mantovani †, Humanitas University
Intersection of Inflammation and Cancer
Lifespan: Hormones, Age, Immunity and Cancer Risk- Population Level Data Sets the Stage
9:00–11:15 AM
JoAnn E. Manson †, Harvard Medical School
Hormones and Cancer Risk: The NHS what does it Teach Us?
Duygu Ucar †, The Jackson Laboratory
Sexual-Dimorphism in Human Immune System Aging
Yin Cao †, Washington University in St. Louis
Aging as a Risk Factor for Cancer
Short Talk(s) Chosen from Abstracts
Coffee Break
9:30–9:50 AM
Workshop: Artificial Intelligence
11:15–12:15 PM
Poster Setup
11:15–1:00 PM
On Own for Lunch
11:15–5:00 PM
Poster Viewing
1:00–10:00 PM
Symposia Spotlight 1: Neuroendocrine Immune Regulation of Cancer - the Host, the Cancer Cell and the Microenvironment
2:30–4:30 PM
Short Talks Chosen from Abstracts
Coffee Available
4:30–5:00 PM
Aging, Sex Differences and Immune Fitness in Cancer Risk AND Treatment
5:00–7:00 PM
Joseph Unger †, Fred Hutchinson Cancer Center
Cancer Outcomes and Sex Differences- Across the Lifespan
Amy Moran, Oregon Health & Science University
Hormones as Immune Modifiers and Determinants of Immunotherapy Outcome
Fabio Conforti †, European Institute of Oncology
Sex Differences in the Efficacy of Immunotherapy for Various Cancers, with Immunotherapy being Less Effective in Women than in Men
Short Talk(s) Chosen from Abstracts
Social Hour with Dinner
7:00–8:00 PM
Posters
7:30–10:00 PM
Sunday, January 3, 2027
Breakfast
7:00–8:00 AM
Life Events: Puberty, Pregnancy, Menopause, and Tumor Development
8:00–11:00 AM
Virginia Borges †, University of Colorado Denver
Talk Title to be Announced
Suzanne D. Conzen, University of Texas Southwestern Medical Center
Pubertal Social Stressors and the Role of Glucocorticoid Receptor in Mammary Gland Development and Cancer Risk
Elizabeth A. Bonney †, University of Vermont
Pregnancy’s Influence on T Cell Regulation
Weiping Zou †, University of Michigan
B7-H4 as a Previously Unrecognized Onco-Fetal Immune Tolerance Checkpoint Driven by Progesterone Signaling
Short Talk(s) Chosen from Abstracts
Coffee Break
9:00–9:20 AM
Poster Setup
11:00–1:00 PM
On Own for Lunch
11:00–5:00 PM
Poster Viewing
1:00–10:00 PM
Career Roundtable
3:00–4:30 PM
Coffee Available
4:30–5:00 PM
Aging in Bone Marrow, the Microenvironment and Immune Fitness vs. Senescence
5:00–7:00 PM
Jennifer Trowbridge †, The Jackson Laboratory
Discovery of Mechanisms by Which the Aging Bone Marrow Microenvironment Drives Progression of Clonal Hematopoiesis to MDS
Stephen S. Chung †, UT Southwestern Medical Center
Aging, Hematopoiesis, Leukemia and the Neuroendocrine Signaling
Robert Cohen †, Calico Life Sciences
Clonal Hematopoiesis (CH): New Genes Linked to Cancer Risk and Aging-Related Phenotype
Short Talk(s) Chosen from Abstracts
Social Hour with Dinner
7:00–8:00 PM
Posters
7:30–10:00 PM
Monday, January 4, 2027
Breakfast
7:00–8:00 AM
Metabolic and Hormonal Changes during Aging as a Driver of Tumorigenesis
8:00–11:00 AM
Ana P. Gomes †, Lee Moffitt Cancer Center & Research Institute
Age-Driven Metabolic and Epigenetic Changes - Metastasis Formation
Ashani T. Weeraratna †, Johns Hopkins University
Sex-Dependent and Epigenetic Effects in the Aged Melanoma Tumor Microenvironment
Marcia C. Haigis †, Harvard Medical School
Age-Associated Contraction of Tumor-Specific T Cells Impairs Antitumor Immunity
Johan Auwerx †, École Polytechnique Fédérale de Lausanne
Nuclear Receptors, Lifespan, Inflammation, Disease, Founded Several Companies
Short Talk(s) Chosen from Abstracts
Coffee Break
9:00–9:20 AM
On Own for Lunch
11:00–5:00 PM
Symposia Spotlight 2: Epigenetics and Cancer Over the Lifespan - Tumor and the Microenvironment
2:30–4:30 PM
Short Talks Chosen from Abstracts
Coffee Available
4:30–5:00 PM
Immunologic Age and Cancer Progression, Therapeutic Responses, and Patient Outcomes
5:00–7:00 PM
Short Talk(s) Chosen from Abstracts
Curtis J. Henry †, University of Colorado Cancer Center
Aging, Obesity, Inflammation and T Cell Function
Daniel Zabransky †, Johns Hopkins School of Medicine
Age-Related Divergence of the Immune Response to Immunotherapy
Zihai Li †, The Ohio State University
Sex Biases and Therapeutic Outcome in ImmunoOncology
Social Hour with Dinner
7:00–8:00 PM
Tuesday, January 5, 2027
Breakfast
7:00–8:00 AM
Aging Immune System, Gene -> Environment (Epigenetics) Interactions: Can we Achieve Better Prevention Over the Lifespan
8:00–11:00 AM
Miriam Merad †, Mount Sinai School of Medicine
Hematopoietic Aging Promotes Cancer by Fueling IL-1⍺-Driven Myelopoiesis
David Furman †, Buck Institute for Research on Aging
Measuring Immune Function in Humans and Machine Learning Tools to Better Define the Role of the Immune System in Disease and Longevity
James V. DeGregori, University of Colorado Denver School of Medicine
Clonal Hematopoiesis and Cancer Prevention
Mark M. Davis †, Stanford University School of Medicine, Howard Hughes
Metrics of Immune Function over the Lifespan
Short Talk(s) Chosen from Abstracts
Coffee Break
9:00–9:20 AM
Meeting Wrap-Up: Outcomes and Future Directions
11:00–11:15 AM
Departure
11:15–11:59 PM

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