Jan 22–25, 2024 | Fairmont Banff Springs, Banff, AB, Canada
Scientific Organizers:
Daniel J. Siegwart and Kathryn Whitehead

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Scientific Organizers: Daniel J. Siegwart and Kathryn Whitehead
Daniel J. Siegwart
Kathryn Whitehead
***Meeting program subject to change.
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Monday, January 22, 2024
Tuesday, January 23, 2024
Delivering the Future of CRISPR-directed Genome Editing
Progress of CRISPR Clinical Programs
In Vivo Base and Prime Editing of Pathogenic Mutations in Mice and Non-Human Primates
Nucleic Acid Delivery Systems for RNA Therapy and Genome Editing
Short Talk: Short Talk: In Utero Gene Editing for a Metabolic Liver Disease in Mice and Nonhuman Primates
Short Talk: Short Talk: CRISPR Engineering and Phenotyping of a Large Isogenic Set of Neurodegeneration-Related Mutations in Human iPSC Models
Targeted Ionizable Lipid Nanoparticles for In Utero Gene Editing of Hematopoietic Stem Cells
In vivo FiCAT Programmable Gene Writing Platform Based on Lipid Nanoparticles Delivery System
Genetically Engineered Transfusable Platelets Using mRNA-Lipid Nanoparticles
A Novel Ligand-siRNA Conjugate Approach to RNAi in Hepatic Stellate Cells
Designing Lipid Nanoparticle Formulations for the Respiratory Tract
Nanoparticle-Mediated Delivery of miR-590-3p Decreases Recurrent GBM Tumor Growth by Inhibits Multiple Oncogenic Nodes
mRNA and the Lung - Progress in Extrahepatic Delivery
A Career of Lipid Nanoparticle Development Leading to the Commercial Success of RNA Therapies
Discovery of Novel Ionizable Lipids for LNP-Mediated Delivery of Therapeutic mRNA
Short Talk: Short Talk: Nature-Inspired mRNA-Based Radioprotectants for Improving Cancer Therapy
Short Talk: Short Talk: Developing Lipid Nanoparticle Formulations for mRNA Delivery in the Brain
Wednesday, January 24, 2024
A Divalent siRNA Chemical Scaffold for Potent and Sustained Modulation of Gene Expression throughout the Central Nervous System
Collagen-assisted Gene Therapy for Regenerative Medicine
Nucleic Acid and Oligonucleotide Delivery for Activating Innate Immunity in Cancer Immunotherapy
Harnessing Endocytosis to Improve the Delivery of Oligonucleotide-Based Drugs
Short Talk: Short Talk: MicroRNA-Targeted Control of Messenger RNA Therapeutic Expression and Immunity
Professor
Group Leader
VP, Head of Research
Principal Investigator
Senior Investigator
Nonviral DNA Delivery to Human Stem Cells
Self-Assembled Polymeric Nanocarriers for Delivery of Nucleic Acid Therapeutics
Short Talk: Short Talk: Focused-Ultrasound Mediated Gene Delivery to Brain Endothelium Without Blood-Brain Barrier Opening
Short Talk: Short Talk: Development of Plasmids for Transcriptionally Targeted Immunological Reprogramming of Hepatocellular Carcinoma with Polymeric Nanoparticles
Short Talk: Short Talk: Durable DNA-based Gene Therapy Using the Non-Viral Fusogenix Proteolipid Vehicle Platform
Short Talk: Short Talk: Development of Novel Triple-Payload Lipid Nanoparticles for Autologous Ex-Vivo Gene Editing
Thursday, January 25, 2024
Mammalian Retrovirus-Like Protein PEG10 Based Delivery Systems for mRNA Delivery and Genome Engineering
Lipid Nanoparticles for mRNA Delivery: The Exquisite Effects of Chemistry on Biological Function
Selective Organ Targeting (SORT) Lipid Nanoparticles (LNPs) for Tissue-Specific Gene Editing
Short Talk: Short Talk: Engineered Neuron Targeting CRISPR RNPs for Improved Genome Editing in the Brain
Short Talk: Short Talk: Development of Immune Modulating Ionizable Lipids and Their Lipid Nanoparticle Formulation for mRNA Vaccines and Therapeutics
Lipid Nanoparticle-Mediated RNA Delivery to Hematopoietic and T-Cells in Humanized Mice and Non-Human Primates
Polymer Nanoparticles for mRNA Delivery
mRNA-LNP Engineering of Donor Platelets is Compatible with Current Blood Banking Practices
Hallmarks of mRNA/LNP Immunogenicity for the Rational Design of Vaccines and Therapeutics
Engineering Domesticated Retroelements for Therapeutic mRNA Delivery
Probing Reactogenicity Mechanisms for Safer mRNA LNP Formulations
Acid degradable lipid nanoparticles efficiently deliver mRNA to multiple organs in vivo
Application of Prime Editing to the Correction of Mutations and Phenotypes in Adult Mice with Liver and Eye Diseases
Delivery of mRNA Vaccines
Friday, January 26, 2024
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