Joint with: Mitochondria Signaling and Disease
Organelle Membrane Contact Sites in Health and Disease
Feb 12–15, 2024 | Fairmont Banff Springs, Banff, AB, Canada
Scientific Organizers:
Gia K. Voeltz and Jodi Nunnari
In Person
On Demand
Feb 12–15, 2024 | Fairmont Banff Springs, Banff, AB, Canada
Scientific Organizers:
Gia K. Voeltz and Jodi Nunnari
Available Formats:
Supported by the Directors' Fund
In Person
On Demand
***Meeting program subject to change.
Available Formats: = In Person = On DemandBooking Function
Fundraising
Merchandise Options
Registration Options
Monday, February 12, 2024
Arrival and Registration
4:00–8:00 PM
Van Horne Foyer
Welcome Mixer
6:00–8:00 PM
Van Horne Foyer
Tuesday, February 13, 2024
Breakfast
7:00–8:00 AM
Mezzanine 2
Welcome and Keynote Session (Joint)
8:00–9:30 AM
Van Horne B
* Heidi M. McBride, McGill University
Session Chair
Session Chair
* Jodi Nunnari, Altos Labs
Session Chair
Session Chair
Karin M. Reinisch, Yale University School of Medicine
Molecular basis for Inter-Organellar Lipid Transfer at Contact Sites
Molecular basis for Inter-Organellar Lipid Transfer at Contact Sites
Edward T. Chouchani, Dana-Farber Cancer Institute
Insights into Dynamic Rewiring of Metabolism in Physiology
Insights into Dynamic Rewiring of Metabolism in Physiology
Coffee Break
9:30–9:50 AM
Van Horne Foyer
Mitochondrial Dynamics (Joint)
9:50–11:15 AM
Van Horne B
* Timothy Wai, Institut Pasteur
Session Chair
Session Chair
* Gia K. Voeltz, University of Colorado Boulder
Session Chair
Session Chair
Luca Scorrano, University of Padova
Unbiased Screenings Illuminate Regulators of Mitochondrial Dynamics and Contact Sites
Unbiased Screenings Illuminate Regulators of Mitochondrial Dynamics and Contact Sites
Stefan Jakobs, Max Planck Institute for Multidisciplinary Sciences
Architecture of Mitochondria
Architecture of Mitochondria
Jodi Nunnari, Altos Labs
Lipid Trafficking at Mitochondria
Lipid Trafficking at Mitochondria
Poster Setup
11:15–1:00 PM
Mezzanine 2
On Own for Lunch
11:15–5:00 PM
Career Roundtable (Joint)
1:00–2:00 PM
Van Horne C
Leon O. Murphy, Casma Therapeutics
Senior Vice President Biology
Senior Vice President Biology
Ana J. García-Sáez, University of Cologne
Professor and Director of the Max Planck Institute of Biophysics
Professor and Director of the Max Planck Institute of Biophysics
Tamas Balla, NICHD, National Institutes of Health
Senior Investigator
Senior Investigator
Dustin Hancks, University of Texas Southwestern Medical Center
Assistant Professor
Assistant Professor
Poster Viewing
1:00–10:00 PM
Mezzanine 2
Workshop 1: Hot Topics in Mitochondrial Biology (Joint)
2:30–4:30 PM
Van Horne B
* Tim Shutt, University of Calgary
Session Chair
Session Chair
Barbora Turpin Knotkova, Heidelberg University
Building Bridges: Reconstitution and Molecular Characterisation of the Mitochondrial Membrane Contact Site
Building Bridges: Reconstitution and Molecular Characterisation of the Mitochondrial Membrane Contact Site
Brandon Chen, University of Michigan
BRD4-Mediated Epigenetic Regulation of Endoplasmic Reticulum-Mitochondria Contact Sites is Governed by Mitochondria Complex III Function
BRD4-Mediated Epigenetic Regulation of Endoplasmic Reticulum-Mitochondria Contact Sites is Governed by Mitochondria Complex III Function
Laurent Chatel-Chaix, Institut National de la Recherche Scientifique
Dengue Virus and Zika Virus Alter Endoplasmic Reticulum-Mitochondria Contacts to Regulate Respiration and Apoptosis
Dengue Virus and Zika Virus Alter Endoplasmic Reticulum-Mitochondria Contacts to Regulate Respiration and Apoptosis
Lena Ho, Duke-NUS Medical School
Microproteins Mediate Localized Mitochondrial Translation to Drive OXPHOS
Microproteins Mediate Localized Mitochondrial Translation to Drive OXPHOS
Marc Germain, Université du Québec à Trois-Rivières
Mitochondria- and ER-Associated Actin are Required for Mitochondrial Fusion
Mitochondria- and ER-Associated Actin are Required for Mitochondrial Fusion
Juan Cruz Landoni, EPFL
Mitochondrial Pearling as a Putative Content Management Mechanism
Mitochondrial Pearling as a Putative Content Management Mechanism
Will Hofstadter, Princeton Universtiy
Infection-Induced Peripheral Mitochondria Fission Drives ER Encapsulations and Inter-Mitochondria Contacts that Rescue Bioenergetics
Infection-Induced Peripheral Mitochondria Fission Drives ER Encapsulations and Inter-Mitochondria Contacts that Rescue Bioenergetics
Coffee Available
4:30–5:00 PM
Van Horne Foyer
Lipid Homeostasis
5:00–7:00 PM
Van Horne C
* Melody Subra, HHMI
Session Chair
Session Chair
Gia K. Voeltz, University of Colorado Boulder
Dynamics of Membrane Contact Sites
Dynamics of Membrane Contact Sites
William A. Prinz, University of Texas Southwestern Medical Center
Lipid Trafficking at the PM
Lipid Trafficking at the PM
Robin Klemm, University of Oxford
Mitochondrial Remodeling During Adipocyte Differentiation
Mitochondrial Remodeling During Adipocyte Differentiation
Kylie N Jacobs, University of Utah
Short Talk: Short Talk: Elucidating Connections Between Amino Acids, Contact Sites, and Lipids in Metabolic Toxicity: a Hidden Gem?
Short Talk: Short Talk: Elucidating Connections Between Amino Acids, Contact Sites, and Lipids in Metabolic Toxicity: a Hidden Gem?
Xing Zeng, UT Southwestern medial center
Short Talk: Short Talk: CLSTN3B Enhances Adipocyte Lipid Droplet Structure and Function via Endoplasmic Reticulum Contact
Short Talk: Short Talk: CLSTN3B Enhances Adipocyte Lipid Droplet Structure and Function via Endoplasmic Reticulum Contact
Social Hour with Lite Bites
7:00–8:00 PM
Mezzanine 2
Poster Session 1
7:30–10:00 PM
Mezzanine 2
Wednesday, February 14, 2024
Breakfast
7:00–8:00 AM
Mezzanine 2
Getting to the Plasma Membrane
8:00–11:00 AM
Van Horne C
* Ryo Higuchi-Sanabria, University of Southern California
Session Chair
Session Chair
Laura L. Lackner, Northwestern University
Tethered to the Plasma Membrane
Tethered to the Plasma Membrane
Jen Liou, University of Texas Southwestern Medical Center
Ca Trafficking at ER-PM Contact Sites
Ca Trafficking at ER-PM Contact Sites
Tamas Balla, NICHD, National Institutes of Health
Moving Lipids
Moving Lipids
Kensuke Tsushima, University of California, Los Angeles
Short Talk: Short Talk: Spatiotemporal Phosphoinositide-AKT Signaling Regulates Myocardial T-tubule and Membrane Dynamics
Short Talk: Short Talk: Spatiotemporal Phosphoinositide-AKT Signaling Regulates Myocardial T-tubule and Membrane Dynamics
Haavard Haukaas, Oslo University Hospital
Short Talk: Short Talk: The PI4K3a Complex: An Active Player at Membrane Contact Sites?
Short Talk: Short Talk: The PI4K3a Complex: An Active Player at Membrane Contact Sites?
Hanlin Zhang, UC Berkeley
Short Talk: Short Talk: The Extracellular Matrix Integrates Mitochondrial Homeostasis to Promote Immunity
Short Talk: Short Talk: The Extracellular Matrix Integrates Mitochondrial Homeostasis to Promote Immunity
Coffee Break
9:00–9:20 AM
Van Horne Foyer
Poster Setup
11:00–1:00 PM
Mezzanine 2
On Own for Lunch
11:00–5:00 PM
Poster Viewing
1:00–10:00 PM
Mezzanine 2
Coffee Available
4:30–5:00 PM
Van Horne Foyer
Molecular Trafficking
5:00–7:00 PM
Van Horne C
* Barbora Turpin Knotkova, Heidelberg University
Session Chair
Session Chair
Pedro Carvalho, University of Oxford
Lipid Droplet Formation
Lipid Droplet Formation
W. Mike Henne, UT Southwestern Medical Center
Lipid Droplet Crosstalk with the Cell Surface
Lipid Droplet Crosstalk with the Cell Surface
György Hajnóczky, Thomas Jefferson University
Moving Calcium Back and Forth
Moving Calcium Back and Forth
Philipp Melchinger, University of Cologne
Short Talk: Short Talk: Identifying Novel Interorganellar Regulators of Adrenal Steroidogenesis
Short Talk: Short Talk: Identifying Novel Interorganellar Regulators of Adrenal Steroidogenesis
Bo Gong, Weill Cornell Medical College
Short Talk: Short Talk: ER-PM Contact Gradients Direct Cell Migration
Short Talk: Short Talk: ER-PM Contact Gradients Direct Cell Migration
Social Hour with Lite Bites
7:00–8:00 PM
Mezzanine 2
Poster Session 2
7:30–10:00 PM
Mezzanine 2
Thursday, February 15, 2024
Breakfast
7:00–8:00 AM
Mezzanine 2
Metabolic Rewiring in Cell Fate Decisions (Joint)
8:00–11:00 AM
Van Horne B
* Mary-Ellen Harper, University of Ottawa
Session Chair
Session Chair
Lydia Finley, Memorial Sloan Kettering Cancer Center
Tuning Cell Fate with Metabolism and Epigenetics
Tuning Cell Fate with Metabolism and Epigenetics
Jessica B. Spinelli, University of Massachusetts Chan Medical School
Unlocking the Potential of the Mammalian Electron Transport Chain
Unlocking the Potential of the Mammalian Electron Transport Chain
Carmela Sidrauski, CalicoLabs
ISR Tuning of Metabolism and Cell Fate in Homeostasis and Disease
ISR Tuning of Metabolism and Cell Fate in Homeostasis and Disease
Fabricio Loayza-Puch, German Cancer Research Center
Short Talk: Short Talk: Exploiting Mitochondrial Translation to Uncover Compartment-specific Metabolic Vulnerabilities
Short Talk: Short Talk: Exploiting Mitochondrial Translation to Uncover Compartment-specific Metabolic Vulnerabilities
Daria Ilatovskaya, Medical College of Georgia
Short Talk: Short Talk: Sex Hormones-mediated Differences in Renal Mitochondrial Bioenergetics and Metabolism
Short Talk: Short Talk: Sex Hormones-mediated Differences in Renal Mitochondrial Bioenergetics and Metabolism
Ryo Higuchi-Sanabria, University of Southern California
Short Talk: Short Talk: Branching Out From Actin Filaments: Actin and Organelle Homeostasis During Aging
Short Talk: Short Talk: Branching Out From Actin Filaments: Actin and Organelle Homeostasis During Aging
Erica Kane, Western Univesity
Short Talk: Short Talk: Interrogating the Mechanistic Role of Integrated Stress Response in Microglial Polarity
Short Talk: Short Talk: Interrogating the Mechanistic Role of Integrated Stress Response in Microglial Polarity
Coffee Break
9:00–9:20 AM
Van Horne Foyer
Poster Setup
11:00–1:00 PM
Mezzanine 2
On Own for Lunch
11:00–5:00 PM
Poster Viewing
1:00–10:00 PM
Mezzanine 2
Workshop 2: Leading Edge Technologies: Mitochondrial Metabolism and Metabolomics (Joint)
2:30–4:30 PM
Van Horne B
* Sara Nowinski, Van Andel Institute
Session Chair
Session Chair
Isshin Shiiba, Gakushuin University
The Development of Organelle Contact Sites Quantification Tool and Exploration of the New Role of ER-Mitochondria Contact
The Development of Organelle Contact Sites Quantification Tool and Exploration of the New Role of ER-Mitochondria Contact
Satoko Shinjo, Fondazione per la ricerca biomedica avanzata VIMM
Imaging Various Interorganellar Distances with STACCATO, a Reversible, Multispectral Split-FAST Mitochondria-ER Contacts Probe
Imaging Various Interorganellar Distances with STACCATO, a Reversible, Multispectral Split-FAST Mitochondria-ER Contacts Probe
Ahmad A. Cluntun, University of Utah, HHMI
MCT1 Facilitates Direct Mitochondrial Oxidation of Lactate in the Heart
MCT1 Facilitates Direct Mitochondrial Oxidation of Lactate in the Heart
Zak Baker, Washington University in St. Louis
Multiomic Profiling Reveals a Critical Role for Triacylgycerol Mobilization in Surmounting Mitochondrial Dysfunction
Multiomic Profiling Reveals a Critical Role for Triacylgycerol Mobilization in Surmounting Mitochondrial Dysfunction
Ana Victoria Lechuga-Vieco, University of Oxford / The Kennedy Institute of Rheumatology
Metabolic Remodeling Through Mitochondrial Transfer: A Key to Enhanced Immune Responses
Metabolic Remodeling Through Mitochondrial Transfer: A Key to Enhanced Immune Responses
Gayathri Muthukumar, Whitehead Institute, MIT
Uncovering Biogenesis Pathways for Alpha-Helical Mitochondrial Outer Membrane Proteins Using Genome-Wide Approaches
Uncovering Biogenesis Pathways for Alpha-Helical Mitochondrial Outer Membrane Proteins Using Genome-Wide Approaches
Coffee Available
4:30–5:00 PM
Van Horne Foyer
Membrane Dynamics
5:00–6:00 PM
Van Horne C
* Kylie N Jacobs, University of Utah
Session Chair
Session Chair
Elizabeth Chen, UT Southwestern Medical Center
The Fusogenic Synapse
The Fusogenic Synapse
Adam Frost, Altos Labs
Mechanisms of Membrane Dynamics
Mechanisms of Membrane Dynamics
Maya B. Schuldiner, Weizmann Institute of Science
New Pathways for Membrane Contact
New Pathways for Membrane Contact
Christina Towers, The Salk Institute for Biological Studies
Metabolic Adaptations to Autophagy Inhibition in Cancer
Metabolic Adaptations to Autophagy Inhibition in Cancer
Meeting Wrap-Up: Outcomes and Future Directions (Organizers)
6:45–7:00 PM
Van Horne C
Social Hour with Lite Bites
7:00–8:00 PM
Mezzanine 2
Poster Session 3
7:30–10:00 PM
Mezzanine 2
Friday, February 16, 2024
Departure
8:00–8:00 AM
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