May 11–14, 2025 | Fairmont Chateau Whistler, Whistler, BC, Canada
Scientific Organizers:
Jose Ordovas-Montanes, Chrysothemis Brown, Karin Pelka, and Jeffrey Moffitt

-
Scientific Organizers: Jose Ordovas-Montanes, Chrysothemis Brown, Karin Pelka, and Jeffrey Moffitt
Jose Ordovas-Montanes
Chrysothemis Brown
Karin Pelka
Jeffrey Moffitt
***Meeting program subject to change.
Available Formats: = In Person = On DemandSunday, May 11, 2025
Fundraising
Booking Function
Merchandise Options
Registration Options
Monday, May 12, 2025
Session Chair
Session Chair
Tissue Archetypes Across Space and Time
Organs-on-Chip Models for Studying Human Pathophysiology
Session Chair
Session Chair
Plasticity in the Tissue Context
Defining, Modeling, and Targeting Cell States in Cancer
Multi-Task Learning for Context-Specific Representations of Cell States
Modeling Cell-State Transitions in the Tissue Niche
Multiscale Delineation of Cellular Interactions in Tissues
Powerful and Accurate Case-Control Analysis of Spatially Resolved Molecular Data
Multimodal Inference of Morphogenomic Phenotypes Using Morphology and Expression Data Optimal Clustering (MEDOC)
MONTAGE: A Computational Framework to Identify Spatially Resolved Functional Enrichment Gradients in the Tissue Microenvironment via Spatial Communities
Unveiling Phenotypic Plasticity in Melanoma: a Novel Computational Approach to Quantify Transcriptional Heterogeneity
Single Cell Spatial Transcriptomics in Mouse Bone Marrow Reveals Age Dependent Cellular Structures
The Power of a Million Cells
Knowledge-Based Computational Approaches to Dissect Multi-Cellular Programs from Single-Cell and Spatial Data
Downstream Impact of Segmentation Errors in Spatial Analysis
Mukin Mouse Ageing Atlas: How Microbiota affects Ageing
Tuesday, May 13, 2025
Lessons Learned from the Single-Cell eQTL Consortium
Charting Inflammatory Disease Trajectories in Human Barrier Tissues
Spatially Organized Multicellular Immune Hubs
Genetic and Infectious Drivers of Human Immune Variation
Examining The Role Of Memory In Intestinal Regeneration
Short Talk: Desynchronization Between Gene Expression And Chromatin Reveals Mechanisms Driving Cell State Change
Senior Scientist-Stanford & Co-Founder-Bullseye Biotechnologies
Senior Scientist
Senior Editor
Session Chair
Session Chair
Remote Presentation: Integrating Single Cell Multiomics and Ancestry to Investigate TB susceptibility
Early Life Development of The Pediatric Duodenum Across Distinct Geographical Environments
Lead Compound Identification Using Live-Cell Imaging of Patient-Derived Endometrial Cancer Organoids
TGFβ2-Driven Iron Dysregulation and Ferroptosis in Salivary Glands Trigger Hyposalivation Under Postmenopausal Conditions
Next-Generation Breast Organoids as a Platform for Studying Human Lactation and Breast Tissue Regeneration
Somatic Mutations in Health and Disease
Novel Antigen Presenting Cells in Early Life Immune Tolerance
Short Talk: Synapse-Seq of Human Immune Cell Interactions Reveals Cytotoxic T Cell Suppression of Autoantibody Production
Manipulating Effector and Memory Fates in CD8+ T cells: a Novel Tpam Transitional State and the Role of TGF-B
Wednesday, May 14, 2025
Remote Presentation: Systematic Perturbation of Cellular Interactions in the Tumor Microenvironment
Community-Based Single-Cell Research
Foundation Models for Target Identifications
Accelerating the Development of Virtual Cells
Short Talk: Highest-Plex Single-Cell Spatial Whole Transcriptome and 1000+ Proteome Identify a New Cell Type and Neural State in Alzheimer’s Disease Brains
Short Talk: Pooled Single-cell CRISPR Screening In Primary Human B Cells Discovers Gene Targets And Pathways Of Non-Coding Autoimmune Risk Loci
Short Talk: High-Resolution Spatial Transcriptomics And Functional Imaging Reveal Cellular Heterogeneity In The Human Pancreas
Identification of a Novel Fibroblast State and Associated Cellular Changes via Local In Vivo Gene Editing in Cancer
Germline- And Non-Germline-Encoded Variation In The TCR Repertoire Impacts Gut-Resident γδ T Cell Activation And Function
A Multimodal Single-Cell Atlas Charts Phenotypic Landscapes Of T Cell Receptor Convergence
Immune Organization In Sentinel Lymph Nodes Of Melanoma Patients Is Prognostic Of Distant Metastases
Photolabile Oligonucleotides Combined with Topologically Imposed Light Gradients Enable Spatially Resolved Single-Cell Transcriptomics and Epigenomics
Single-Cell Enhancerome Profiling Identifies Key Transcriptional Regulators of Human Tumor-Infiltrating Treg Cells
SPanC-Lnc : Decoding the Spatial and Single Cell Landscape of Long Non-coding RNAs at a Pan-Cancer Level
Pericytes Promote Multiple Mechanisms of Cardiac Organoid Optimization for Cardiac Regeneration
Session Chair
From Correlation to Causation: Improving Human Disease Representation in vitro for Functional Testing of in vivo-Derived Hypotheses
Single-Cell Phenoscaping of Tumour Microenvironment Organoids
The Role of Spatial Organization in the Gut-Microbiome Interface in Gut Inflammation
Short Talk: Multi-Omics Immune Profiling of Graft-Versus-Host Disease (GvHD) In Humans
Thursday, May 15, 2025
Subscribe for Updates