Jan 16–19, 2024 | Beaver Run Conference Center, Breckenridge, CO, United States
Scientific Organizers:
Linde Meyaard, Jonathon D. Sedgwick, Carla V. Rothlin, and Alex McCarthy

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Scientific Organizers: Linde Meyaard, Jonathon D. Sedgwick, Carla V. Rothlin, and Alex McCarthy
Linde Meyaard
Jonathon D. Sedgwick
Carla V. Rothlin
Alex McCarthy
***Meeting program subject to change.
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Tuesday, January 16, 2024
Wednesday, January 17, 2024
Session Chair
Inhibitory Receptors and Microbiome Regulation of the Anti-Cancer Immune Response
Session Chair
CTLA-4 Blockade Drives the Naïve B Cell Repertoire Towards Autoimmunity
Regulation of Mast Cells and Eosinophils by Inhibitory Receptors in Allergy
CLEC12A Regulation of Neutrophil Activation in Chronic Inflammatory Diseases
Session Chair
A Novel Bioinformatics Pipeline for the Identification of Immune Inhibitory Receptors as Potential Therapeutic Targets
Streptococcus Pyogenes Interacts with the Human Inhibitory Receptor LILRB2
CTLA-4 Transendocytosis of CD80, but Not Simple CD80-CTLA-4 Binding, Regulates PD-L1:PD-1 Interactions
GSK-3 Signaling Affects T-cell Homeostasis that Enables CD8 Super-armed Killers in Anti-PD-1 Immunotherapy
PD-1H/VISTA Agonism as a Potential Therapy for Autoimmune Skin Diseases
TCR Ligand Potency Differentially Regulates PD-1-Mediated Inhibitions
Identification and Characterization of Inhibitory Receptor Agonists for the Treatment of Autoimmune and Inflammatory Diseases
Session Chair
Session Chair
Selective Anti-SIRPa Targeting in Immuno-Oncology
Checkpoint Blockade by Phosphatase Recruitment
Regulation of Myeloid Cell Biology Through the ILT/LILRB Inhibitory Receptors
Short Talk: Short Talk: Degradation of Siglec-7/-9 Receptors Rejuvenates T Lymphocytes in Cancer Immunotherapy
Short Talk: Short Talk: Identification of OSCAR as a LAIR1-Regulated Receptor Mediating Collagen-Induced Myeloid Inflammation
Thursday, January 18, 2024
Session Chair
Remote Presentation: Unlocking the Therapeutic Potential of Glycobiology
Inhibitory Pattern Recognition Receptors in Homeostasis
Unveiling the Power of Phagocytic Receptor Specificity to Explore Macrophage Functions
MERTK and TYRO3 in Retinal Homeostasis
Short Talk: Short Talk: The Inhibitory Role of Cell Surface PILRα–CD8α Interactions in Maintaining Cd8+ T Cell Quiescence and Homeostasis
Short Talk: Short Talk: Siglec-E is a Novel Co-inhibitory Receptor in the Modulation of Innate Activation after Transplantation
Associate Professor
Professor
Executive Director
Session Chair
Session Chair
Identification of Novel Inhibitory Receptor Interactions
KIRs, T Cell Dynamics, Control of Chronic Virus Infection and Autoimmunity
TREM2 and AXL in Neurodegeneration
Short Talk: Short Talk: SHP-1 Negatively Regulates Microglial Innate Immune Responses in Aβ Amyloidosis
Friday, January 19, 2024
Session Chair
Regulation of Epithelium by CEACAMs
TIGIT Limits Immune Pathology During Viral Infections
Immune Evasion of Plasmodium falciparum via Inhibitory Receptors
CD47 Ligation Repositions the Inhibitory Receptor SIRPA to Suppress Integrin Activation and Phagocytosis
Short Talk: Short Talk: LAIR1 Prevents Excessive Inflammatory Signaling in S. Aureus Skin and Soft Tissue Infection
Session Chair
Investigation of the Role of CD300a in Epstein–Barr Virus-infected B Cells and its Potential as a Target Antigen for T Cell-redirecting Bispecific Antibodies
Single Protein Mapping of Immune Checkpoints Reveals CD80 as an Antagonist of PD-L1/MHC-I Clusters
Location-Specific T-cell Inhibitory Molecules (LoSTIMs)
Surface Removal and Degradation of PD-L1 Using SureTACs Technology
CD47 Promotes Peripheral T Cell Survival by Preventing Dendritic Cell–mediated T Cell Necroptosis
PD-1 Safeguards Against Cutaneous Immunopathology by Local Neoantigen-specific CD8 T Cells
Agonizing Multiple Inhibitory Receptors: A Potential Therapeutic Strategy for Autoimmune Diseases
Regulation of Neutrophil Extracellular Trap Formation by a Novel Inhibitory C-type Lectin Receptor
Session Chair
Session Chair
Clinical Validation of Checkpoint Agonist Antibodies in Immunologic Disease
Selection of Checkpoint agonist Antibodies through Understanding of Inhibitory Receptor Signaling
Current Status and the Future Promise for Therapeutic Inhibitory Receptor Targeting
Saturday, January 20, 2024
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