DNA Replication: Pathway Crosstalk Shaping Physiology and Disease

Apr 05–08, 2027 | Mercure London Earls Court, London, United Kingdom
Scientific Organizers: Karlene A Cimprich, Alessandro Vindigni, and Massimo Lopes

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Apr 05–08, 2027 | Mercure London Earls Court, London, United Kingdom

Scientific Organizers: Karlene A Cimprich, Alessandro Vindigni, and Massimo Lopes

Supported by the  Directors' Fund

***Meeting program subject to change.

Available Formats:   = In Person     = On Demand
Monday, April 5, 2027
Registration
4:00–8:00 PM
Welcome Mixer
6:00–8:00 PM
Tuesday, April 6, 2027
Breakfast
7:30–8:30 AM
Poster Setup
8:00–8:30 AM
Poster Viewing
8:15–5:00 PM
Welcome Remarks
8:30–8:40 AM
Keynote Address
8:40–9:30 AM
John F.X. Diffley, Francis Crick Institute
40 Years of DNA Replication
DNA Replication and Repair
9:30–11:45 AM
Jo R. Morris, University of Birmingham
New Recombination/Replication Interface
Roger Greenberg, University of Pennsylvania
Break-Induced Replication
Vincenzo Costanzo, IFOM
Replication-Coupled Repair
Short Talk(s) Chosen from Abstracts
Coffee Break
10:00–10:20 AM
Lunch
11:45–12:45 PM
Posters
12:30–2:30 PM
Symposia Spotlight 1: Late-breaking research presentations selected from abstract submissions
2:30–4:30 PM
Short Talks Chosen from Abstracts
Coffee Available
4:30–5:00 PM
DNA Replication and Transcription
5:00–7:00 PM
Stephan Hamperl †, Helmholtz-Zentrum Munich
Resolving Transcription-Replication Conflicts
Martijn Luijsterburg †, Leiden University Medical Center
Transcription-Coupled Repair Mechanisms
Karlene A Cimprich, Stanford University
DNA:RNA Hybrids: Processing and Signaling
Short Talk(s) Chosen from Abstracts
On Own for Dinner
7:00–8:00 PM
Wednesday, April 7, 2027
Breakfast
7:30–8:30 AM
Poster Setup
8:00–8:30 AM
Poster Viewing
8:15–5:00 PM
DNA Replication across DNA Damage
8:30–11:30 AM
Priyanka Verma †, Washington University
Replication of DNA Adducts
Kasper Fugger, University College London
Nucleotide Metabolism and Replication Stress
Puck Knipscheer †, Hubrecht Institute
Replication across DNA Crosslinks
Alessandro Vindigni, Washington University
Mechanisms of Replication Fork Restart Upon Cancer Therapies
Short Talk(s) Chosen from Abstracts
Coffee Break
9:30–9:50 AM
Lunch
11:30–12:30 PM
Posters
12:30–2:30 PM
Career Roundtable
3:00–4:30 PM
Coffee Available
4:30–5:00 PM
DNA Replication, Metabolism and Inflammation
5:00–7:00 PM
Philippe Pasero, Institute of Human Genetics
Fork Resection and Inflammatory Signaling
Agnel Sfeir, Memorial Sloan Kettering Cancer Center
Polθ Channels Replication-Induced DNA Breaks into Microhomology-Mediated Repair
Lorenza Penengo, University of Zurich
Interferon Responses and DNA Replication Stress
Short Talk(s) Chosen from Abstracts
On Own for Dinner
7:00–8:00 PM
Thursday, April 8, 2027
Breakfast
7:30–8:30 AM
DNA Replication, Chromatin and Nuclear Dynamics
8:30–11:30 AM
Jiazhi Hu, Peking University
The Impact of Chromatin Structure on DNA Replication
Nynke H. Dekker †, University of Oxford
Nucleosomes and Condensability of Nascent DNA
Peter Ly, University of Texas Southwestern Medical Center
Replication of Cytoplasmic Chromosomes in Micronuclei
Nitika Taneja, Erasmus Medical Center
Chromatin Organization in the Replication Stress Response
Short Talk(s) Chosen from Abstracts
Coffee Break
9:30–9:50 AM
Meet the Editors
11:30–12:30 PM
Lunch
12:30–1:30 PM
Symposia Spotlight 2: Late-breaking research presentations selected from abstract submissions
2:30–4:30 PM
Short Talks Chosen from Abstracts
Coffee Available
4:30–5:00 PM
DNA Replication Plasticity in Physiology and Disease
5:00–6:15 PM
Agata Smogorzewska, Rockefeller University
Living with DNA Damage: Consequences of Replication-Associated Defects for Human Health
Massimo Lopes, University of Zürich
Tissue-Specific Replication Fork Plasticity
Short Talk(s) Chosen from Abstracts
Closing Keynote Address
6:15–7:00 PM
Johannes C. Walter, Harvard Medical School
Coordination of Replication and Repair by Disease-Related Factors
Meeting Wrap-Up: Outcomes and Future Directions
7:00–7:15 PM
On Own for Dinner
7:15–8:15 PM
Friday, April 9, 2027
Departure
12:00–11:59 PM

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