Long COVID and Other Post-Acute Infection Syndromes
Aug 10–13, 2025 | Eldorado Hotel & Spa, Santa Fe, NM, United States
Scientific Organizers:
Akiko Iwasaki, Avindra Nath, Hannah Davis, and Daniel M. Altmann
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Aug 10–13, 2025 | Eldorado Hotel & Spa, Santa Fe, NM, United States
Scientific Organizers: Akiko Iwasaki, Avindra Nath, Hannah Davis, and Daniel M. Altmann
Akiko Iwasaki, PhD
Yale University/HHMI
Akiko Iwasaki, Ph.D., is a Sterling Professor of Immunobiology and Molecular, Cellular, and Developmental Biology at Yale University, and an Investigator of the Howard Hughes Medical Institute. She received her Ph.D. from the University of Toronto in Canada and her postdoctoral training from the National Institutes of Health. Her research focuses on the mechanisms of immune defense against viruses at the mucosal surfaces, and the development of mucosal vaccine strategies. She is the co-Lead Investigator of the Yale COVID-19 Recovery Study, which aims to determine the changes in the immune response of people with long COVID after vaccination. Dr. Iwasaki also leads multiple other studies to interrogate the pathobiology of long COVID, both in patients, and through developing animal models of long COVID. Dr. Iwasaki was elected to the National Academy of Sciences in 2018, to the National Academy of Medicine in 2019, to the European Molecular Biology Organization in 2021, and to the American Academy of Arts and Sciences in 2021.
Avindra Nath, MD
NINDS, National Institutes of Health
Dr. Nath received his MD degree from Christian Medical College in India in 1981 and completed a residency in Neurology from University of Texas Health Science Center in Houston, followed by a fellowship in Multiple Sclerosis and Neurovirology at the same institution and then a fellowship in Neuro-AIDS at NINDS. He held faculty positions at the University of Manitoba (1990-97) and the University of Kentucky (1997-02). In 2002, he joined Johns Hopkins University as Professor of Neurology and Director of the Division of Neuroimmunology and Neurological Infections. He joined NIH in 2011 as the Clinical Director of NINDS, the Director of the Translational Neuroscience Center and Chief of the Section of Infections of the Nervous System. His research focuses on understanding the pathophysiology of retroviral infections of the nervous system and the development of new diagnostic and therapeutic approaches for these diseases.
Hannah Davis
Hannah E. Davis, MPS is an American artist, data scientist and long COVID researcher. She was one of the founders of the Patient-Led Research Collaborative (PLRC), a group of long COVID patients with experience in research or data analysis. Research early in the COVID-19 pandemic by the PLRC mapped how a COVID-19 infection could have long-term debilitating effects, even for young and previously healthy people. It was used for the CDC's documentation on long COVID. Davis studied international relations, and later spent time in Ghana. For her masters, she studied creative communication technology at New York University.
Daniel M. Altmann, PhD
Imperial College London
Danny Altmann, PhD heads a lab at the Hammersmith Hospital Campus of Imperial College of London, with expertise in the HLA system, antigen discovery, T cell subsets and NK cells. Key research interests are the immunology of infectious disease including severe bacterial infections, Zika virus and Chikungunya virus. Other projects focus on autoimmune disease including the role of the microbiota in rheumatoid arthritis and autoimmune immunotoxicity in cancer immunotherapy. He is editor-in-chief of Oxford Open Immunology. For 20 years, Altmann was editor of British Society for Immunology (BSI) journals, including 14-years as editor-in-chief at Immunology, and is an associate editor at Vaccine and Frontiers in Immunology. Altmann is a trustee of the Medical Research Foundation. He has sat on the Strategy Board of the African Research Excellence Fund since its inception.
Altmann earned a bachelor's degree from the University of London in 1980, and a PhD from the University of Bristol in 1983 on T cell immunity to herpesviruses.
Altmann earned a bachelor's degree from the University of London in 1980, and a PhD from the University of Bristol in 1983 on T cell immunity to herpesviruses.
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In Person
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***Meeting program subject to change.
Available Formats: = Livestream = In Person = On DemandSunday, August 10, 2025
Booking Function
Merchandise Options
Registration Options
Registration
4:00–8:00 PM
Concourse
Welcome Mixer
6:00–8:00 PM
Cava Santa Fe
Monday, August 11, 2025
Breakfast
7:00–8:00 AM
Anasazi Ballroom
Poster Setup
7:30–8:00 AM
Anasazi Ballroom
Poster Viewing
7:30–5:00 PM
Anasazi Ballroom
Welcome and Keynote Address
8:00–9:00 AM
Eldorado Ballroom
* Akiko Iwasaki, Yale University/HHMI
* Hannah Davis, Patient-Led Research Collaborative
Michael J Peluso, University of California, San Francisco
Insights from LIINC Study and Monoclonal Antibody Trial
Insights from LIINC Study and Monoclonal Antibody Trial
Epidemiology, Clinical Diagnosis and Management of Long COVID
9:00–11:15 AM
Eldorado Ballroom
* Hannah Davis, Patient-Led Research Collaborative
Long COVID: Major Findings, Mechanisms and Recommendations
Long COVID: Major Findings, Mechanisms and Recommendations
Ziyad Al-Aly, Washington University School of Medicine
Epidemiology of Long COVID
Epidemiology of Long COVID
David Putrino, Mount Sinai School of Medicine
Clinical Diagnosis and Management of Long COVID
Clinical Diagnosis and Management of Long COVID
Michelle J L Scoullar, Burnet Institute
Short Talk: A Narrative Review of the Impact, Treatment and Outcomes of Paediatric Long COVID, Including the Prevalence of Dysautonomia, From A Specialist Long COVID Clinic in Australia
Short Talk: A Narrative Review of the Impact, Treatment and Outcomes of Paediatric Long COVID, Including the Prevalence of Dysautonomia, From A Specialist Long COVID Clinic in Australia
Coffee Break
9:30–9:50 AM
Concourse
Lunch
11:15–12:15 PM
Anasazi Ballroom
Women in Science Networking Session
11:20–12:15 PM
Eldorado Ballroom
Poster Session 1
11:45–2:15 PM
Anasazi Ballroom
Symposia Spotlight: Featured Abstract Presentations
2:15–4:30 PM
Anasazi Ballroom
Amelie Bos, University Medical Centre Amsterdam
An In Vitro Model for Long-COVID Using Skeletal Muscle Cultures and Patient Plasma
An In Vitro Model for Long-COVID Using Skeletal Muscle Cultures and Patient Plasma
* Timothy J. Henrich, University of California, San Francisco
Multi-Omic Analysis of Bone Marrow from People with and Without Long COVID Reveals Lymphoproliferative Disorders and Immune Dysregulation but Not SARS-CoV-2 Persistence
Multi-Omic Analysis of Bone Marrow from People with and Without Long COVID Reveals Lymphoproliferative Disorders and Immune Dysregulation but Not SARS-CoV-2 Persistence
Penelope Markham, BioVie
A Phase 2 Trial Designed to Enhance Signal Detection in an Evaluation of Bezisterim (NE3107) For the Treatment of Neurological Symptoms of Long COVID
A Phase 2 Trial Designed to Enhance Signal Detection in an Evaluation of Bezisterim (NE3107) For the Treatment of Neurological Symptoms of Long COVID
Claire S Laxton, Yale University
Development of a Multiplex qPCR To Detect Herpesvirus Reactivation and Shedding Dynamics in Saliva of Long Covid Patients
Development of a Multiplex qPCR To Detect Herpesvirus Reactivation and Shedding Dynamics in Saliva of Long Covid Patients
Emma Wall, The Francis Crick Institute
An Innate Inflammatory Signature Is Consistently Enriched in the Plasma of Adults Living with Long COVID Across all Clinical Symptom Groups
An Innate Inflammatory Signature Is Consistently Enriched in the Plasma of Adults Living with Long COVID Across all Clinical Symptom Groups
Nadia R. Roan, University of California, San Francisco
Inhibition of CXCR4 Signaling Reverses Behavioral Abnormalities in a Mouse Model of Long COVID
Inhibition of CXCR4 Signaling Reverses Behavioral Abnormalities in a Mouse Model of Long COVID
Esther Melamed, Dell Medical School
Analysis of 977 Long COVID Patients Reveals Prevalent Neuropathy and Association with Anti-Ganglioside Antibodies
Analysis of 977 Long COVID Patients Reveals Prevalent Neuropathy and Association with Anti-Ganglioside Antibodies
Michela Locci, University of Pennsylvania
Alterations of B Cell Responses to SARS-CoV-2 in Long COVID
Alterations of B Cell Responses to SARS-CoV-2 in Long COVID
Hung-Jen Chen, University of Amsterdam, Amsterdam University Medical Centers
Long COVID and Autoimmunity: Transfer of IgG from Long COVID Patients Induces Symptomology in Mice
Long COVID and Autoimmunity: Transfer of IgG from Long COVID Patients Induces Symptomology in Mice
Coffee Available
4:30–5:00 PM
Concourse
Immunological Dysfunction and Mechanisms of Long COVID
5:00–7:00 PM
Eldorado Ballroom
* Daniel M. Altmann, Imperial College London
Immune Signatures of Long COVID
Immune Signatures of Long COVID
E. John Wherry, University of Pennsylvania
Using T Cells as Biosensors in Long COVID
Using T Cells as Biosensors in Long COVID
Akiko Iwasaki, Yale University/HHMI
Immunological Mechanisms of Long COVID
Immunological Mechanisms of Long COVID
August Jernbom, KTH Royal Institute of Technology / Johns Hopkins University
Short Talk: Prevalent and Persistent New-Onset Autoantibodies in Mild to Severe COVID-19
Short Talk: Prevalent and Persistent New-Onset Autoantibodies in Mild to Severe COVID-19
Shubha Talwar, Imperial College London
Short Talk: Investigating the Role of Autoantibodies in Long-Lasting Respiratory Symptoms Post-COVID-19
Short Talk: Investigating the Role of Autoantibodies in Long-Lasting Respiratory Symptoms Post-COVID-19
On Own for Dinner
7:00–8:00 PM
Tuesday, August 12, 2025
Breakfast
7:00–8:00 AM
Anasazi Ballroom
Post-Acute Infection Syndromes
8:00–10:30 AM
Eldorado Ballroom
Lisa F.P. Ng, Infectious Diseases Labs, ASTAR
Post-Chikungunya Virus Autoimmune Syndrome
Post-Chikungunya Virus Autoimmune Syndrome
Michal Caspi Tal, Massachusetts Institute of Technology
Unraveling the Immunopathology of Borrelia Infection-Associated Chronic Illnesses: Sex Differences and Predictive Diagnostics
Unraveling the Immunopathology of Borrelia Infection-Associated Chronic Illnesses: Sex Differences and Predictive Diagnostics
* Maureen R. Hanson, Cornell University
Immune Signaling in ME/CFS
Immune Signaling in ME/CFS
Jalene Velazquez, Washington State University
Short Talk: Distinct Antibody Effector Profiles Track with the Development of Post-Ebola Syndrome
Short Talk: Distinct Antibody Effector Profiles Track with the Development of Post-Ebola Syndrome
Maia M Madison, UCSF
Short Talk: Cytokine Biomarkers for Differential Diagnosis of Persistent Lyme Disease and Other Infection-Associated Chronic Illnesses
Short Talk: Cytokine Biomarkers for Differential Diagnosis of Persistent Lyme Disease and Other Infection-Associated Chronic Illnesses
Coffee Break
9:00–9:20 AM
Concourse
Poster Setup
11:00–1:00 PM
Anasazi Ballroom
On Own for Lunch
11:00–3:00 PM
Poster Viewing
1:00–10:00 PM
Anasazi Ballroom
Career Roundtable
1:45–2:45 PM
Eldorado Ballroom
Panel Discussion: Long COVID: Mechanisms, Diagnosis, and Emerging Treatments
3:00–4:30 PM
Eldorado Ballroom
* Sten H. Vermund, University of South Florida
Akiko Iwasaki, Yale University/HHMI
Anders G. Vahlne, Karolinska Institutet
Resia Pretorius, Stellenbosch University
Janet M Mullington, BIDMC & Harvard Medical School
Annukka A Antar, Johns Hopkins School of Medicine
Coffee Available
4:30–5:00 PM
Concourse
Gut, Sex and other Influences on the Manifestation of PAIS
5:00–7:00 PM
Eldorado Ballroom
Maayan Levy, Stanford University
The Role of Persistent Gut Infection in Long COVID
The Role of Persistent Gut Infection in Long COVID
* Sabra L. Klein, Johns Hopkins University
Sex Differences in Long COVID Revealed by Animal Models
Sex Differences in Long COVID Revealed by Animal Models
Vivian Vasconcelos C Litwinski, Federal University of Minas Gerais
After the Virus: Mechanisms Driving Post-Viral Sequelae
After the Virus: Mechanisms Driving Post-Viral Sequelae
Brian H LaFranchi, UCSF
Short Talk: Deep Multi-Omic Analysis of Colorectal Tissues from People with and Without Long COVID Demonstrates SARS-CoV-2 Persistence and Immune Dysregulation Years After Initial Infection
Short Talk: Deep Multi-Omic Analysis of Colorectal Tissues from People with and Without Long COVID Demonstrates SARS-CoV-2 Persistence and Immune Dysregulation Years After Initial Infection
James Chung, University of Missouri
Short Talk: Facilitating Mouse Studies of Long COVID
Short Talk: Facilitating Mouse Studies of Long COVID
Social Hour with Dinner
7:00–8:00 PM
Anasazi Ballroom
Poster Session 2
7:30–10:00 PM
Anasazi Ballroom
Wednesday, August 13, 2025
Breakfast
7:00–8:00 AM
Anasazi Ballroom
Neurological and Vascular Damages in Long COVID
8:00–11:00 AM
Eldorado Ballroom
* Avindra Nath, NINDS, National Institutes of Health
Neurological Complications in Long COVID and ME CFS
Neurological Complications in Long COVID and ME CFS
Jennifer Frontera, New York University
Neurodegenerative Diseases Following COVID-19
Neurodegenerative Diseases Following COVID-19
Petter Brodin, Karolinska Institutet
Viral Persistence and Regulation of Immunity in PACS
Viral Persistence and Regulation of Immunity in PACS
Joga R. Chaganti, Thomas Jefferson University Hospital
Imaging Correlates of Dysfunction in Glymphatic System, Blood Brian Barrier and Explore Glutamatergic Excitotoxicity in Long Covid
Imaging Correlates of Dysfunction in Glymphatic System, Blood Brian Barrier and Explore Glutamatergic Excitotoxicity in Long Covid
Lindsay McAlpine, Yale University School of Medicine
Short Talk: Cerebrospinal Fluid Alterations & Proteomics in Neuropsychiatric Long COVID
Short Talk: Cerebrospinal Fluid Alterations & Proteomics in Neuropsychiatric Long COVID
Alba Azola, Johns Hopkins School of Medicine
Short Talk: Blood-Brain Barrier Disruption in Long COVID and Cognitive Correlates
Short Talk: Blood-Brain Barrier Disruption in Long COVID and Cognitive Correlates
Coffee Break
9:00–9:20 AM
Concourse
Poster Setup
11:00–1:00 PM
Anasazi Ballroom
On Own for Lunch
11:00–2:15 PM
Poster Viewing
1:00–10:00 PM
Anasazi Ballroom
Understudied Topics in PAIS
2:30–4:30 PM
Eldorado Ballroom
Roshan Kumar, HiFiBiO Therapeutics
T Cell Dysregulation Revealed by Single-Cell TCR Repertoire & Expression Profiling of Long COVID and ME/CFS Patients
T Cell Dysregulation Revealed by Single-Cell TCR Repertoire & Expression Profiling of Long COVID and ME/CFS Patients
Hideki Ueno, Graduate School of Medicine, Kyoto University
Sex Differences in Immune Responses Shape Long COVID Pathogenesis
Sex Differences in Immune Responses Shape Long COVID Pathogenesis
Cherie L Marvel, Johns Hopkins University
Functional brain imaging and outcomes in long COVID and post treatment Lyme disease
Functional brain imaging and outcomes in long COVID and post treatment Lyme disease
Paige Hansen Colburn, Massachusetts Institute of Technology
Lyme Disease Increases Risk for Multiple Gynecological Conditions
Lyme Disease Increases Risk for Multiple Gynecological Conditions
* John N Aucott, Johns Hopkins University
The Concurrence of Post-Treatment Lyme Disease, Fibromyalgia, and ME/CFS
The Concurrence of Post-Treatment Lyme Disease, Fibromyalgia, and ME/CFS
Bronwyn M Gunn, Washington State University
Humoral Immune Correlates of Orthoebolavirus Sudanese RNA Persistence in Semen
Humoral Immune Correlates of Orthoebolavirus Sudanese RNA Persistence in Semen
Abigail Vanderheiden, Washington University in St. Louis
Dural CD4+ T Cells Promote Hippocampal Memory Deficits in a Mouse Model of COVID-19
Dural CD4+ T Cells Promote Hippocampal Memory Deficits in a Mouse Model of COVID-19
Bornali Bhattacharjee, Yale University
Immunological and Antigenic Signatures Associated with Chronic Illnesses after COVID-19 Vaccination
Immunological and Antigenic Signatures Associated with Chronic Illnesses after COVID-19 Vaccination
Coffee Available
4:30–5:00 PM
Concourse
Clinical and Translational Approaches in PAIS
5:00–6:15 PM
Eldorado Ballroom
* E. Wesley Ely, Vanderbilt University Medical Center
Reverse-LC Baricitinib Trial for Long COVID
Reverse-LC Baricitinib Trial for Long COVID
Amitava Banerjee, University College London
Insights from STIMULATE-ICP
Insights from STIMULATE-ICP
Giulia Unali, Boston University
Short Talk: Bone Marrow Hematopoietic Impairment in a Humanized Mouse Model of Post-acute Sequelae of COVID-19
Short Talk: Bone Marrow Hematopoietic Impairment in a Humanized Mouse Model of Post-acute Sequelae of COVID-19
Meeting Wrap-Up: Outcomes and Future Directions
6:15–6:30 PM
Eldorado Ballroom
Social Hour with Dinner
6:30–7:30 PM
Anasazi Ballroom
Poster Session 3
7:30–10:00 PM
Eldorado Ballroom
Thursday, August 14, 2025
Departure
12:00–11:59 PM
Fundraising
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