Jun 08–11, 2025 | Whistler Conference Centre, Whistler, BC, Canada
Scientific Organizers:
Dorothy Schafer, Asya Rolls, and Anne Schaefer

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Scientific Organizers: Dorothy Schafer, Asya Rolls, and Anne Schaefer
Dorothy Schafer
Asya Rolls
Anne Schaefer
***Meeting program subject to change.
Available Formats: = Livestream = In Person = On DemandMerchandise Options
Registration Options
Sunday, June 8, 2025
Fundraising
Booking Function
Monday, June 9, 2025
Neuronal Circuits of Sickness and Social Behavior
Development of Epigenetic Modifiers for Discovery Research and Neurodegenerative Disease Therapies
Session Chair
Accumulation of dysfunctional oligodendrocytes in human cognitive decline with aging
Therapeutic Targeting of Microglial Inflammatory Responses within Diseased Brain Circuits
The SARM1 Axon Degeneration Pathway: Mechanistic Insights Drive Therapeutic Opportunities
Session Chair
Integrating iPSC-Based Models, Genomics, And Machine Learning To Uncover Neurological Disease Mechanisms And Therapeutic Targets
Global Organelle Profiling: Combining Stem Cell Models and Proteomics to Uncover Variant-Specific Disease Mechanism in Neurodegenerative Diseases
Optoproteomics: Unbiased Spatial Proteomics for Neurodegenerative Diseases
Soma-seq: Intracellular CITE-seq in Frozen Human Brain Tissue Enables the Discovery of Proteinopathy-Associated Gene Expression Signatures
Recurrent Patterns of Widespread Neuronal Genomic Damage Shared by Major Neurodegenerative Disorders
Session Chair
Alzheimer’s Disease Reveals Regulatory Microglia Potential
Microglia Control Circuit Homeostasis and Pathological States
The Brain Vasculature: A Conduit between the Periphery and Control of Brain Circuits
Astrocyte Control of Neural Circuits During Inflammation
Tuesday, June 10, 2025
Session Chair
The Impact of Aging on Remyelination Potential in the Inflamed Brain
Role of cGAS/Sting in Neurodegenerative Diseases
Age-Related Translational and Ribosomal Dysfunction and its Contribution to Neurodegeneration
Short Talk: Decoding Regional Drivers of Microglia Aging via Heterochronic Myeloid Cell Replacement
Short Talk: Synaptic Proteins with Age-Related Proteostasis Aberrations Accumulate in Microglia
Short Talk: Enhancer Deletion of a Microglial-Specific AD BIN1 Risk Variant Alters Lysosomal Phenotype and DAM Response in Ipsc-Derived Microglia
Short Talk: Targeting Cellular Metabolism to Modulate Microglial Function in Health and Disease
Assistant Professor
Senior Principal Scientist
Principal, Dementia Discovery Fund
Senior Editor
*Session Chair, Scientific Editor, Neuron
Chief Editor
Senior Scientific Editor
Executive Editor, CSHL Press
Associate Editor
Session Chair
Immunoception- Neuronal Representation of Immune Processes to Modulate Behavior
Stress-Induced Regulation of Immune System Function
Neural Control of the Peripheral Immune Response
Short Talk: Uncovering the Role of Circumventricular Organs During Infection
Wednesday, June 11, 2025
Session Chair
Neural Control of Age-Related Metabolic Dysfunction
Neural Networks Controlling Peripheral Organ Function
Neuroimmune Control of Obesity
Short Talk: Leptin Signaling Maintains Autonomic Stability During Severe Influenza Infection in Mice
Short Talk: Monocyte-derived IL-10 Drives Sex Difference in Pain Duration
Short Talk: A Gut-Immune-Brain Circuit Links Diet-Induced Microbial Dysbiosis to Sleep Disruption
Session Chair
Remote Presenter: Exploring the Interaction between Blood Plasma Proteins and Microglia: Insights into Brain-Peripheral Communication
Remote Presenter: Monocytes Mobilized by Enteric Neurons Remodel the Enteric Nervous System
Remote Presenter: The Role of Macrophage Metabolic Reprogramming in Peripheral Nervous System Regeneration and Development of Neuropathic Pain
Remote Presenter: Maternal Immune Activation Reveals Male-Specific Sensitivity to Inflammation-Driven Deficits in Fetal Development
Early-Life Gut Inflammation Drives Sex-Dependent Shifts in the Microbiome-Endocrine-Microglia Axis
Astrocyte Precursor Cells Instruct Microglial Programming Via IL-3 For Neuronal Sculpting And Social Development
The Transcription Factor RXRɑ, Regulates the Disease-Associated Gene Signatures of Myeloid Cells in Immune-Mediated OCD
Neuro-Immune Signaling Underlying Behavioral Fever in Larval Zebrafish
Session Chair
Neural-Immune Signaling Governing Microglia Function Within Brain Circuits
Understanding the Bi-Directional Communication Between the Gut and the Brain
Immune Environment in Brain Borders Governing Circuit Function and Behavior
Short Talk: Protozoan Parasite Disrupts Intestinal Immunity in Pregnancy, Thalamocortical Activity in Offspring
Thursday, June 12, 2025
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