Fueling MASH: Metabolic Drivers and Inflammatory Crosstalk
Apr 12–15, 2026 | Fairmont Hotel Vancouver, Vancouver, BC, Canada
Scientific Organizers:
Utpal B. Pajvani, Jennifer L. Estall and Ariel E. Feldstein
Apr 12–15, 2026 | Fairmont Hotel Vancouver, Vancouver, BC, Canada
Scientific Organizers:
Utpal B. Pajvani, Jennifer L. Estall and Ariel E. Feldstein
Available Formats:
Supported by the Directors' Fund
Livestream
In Person
On Demand
***Meeting program subject to change.
Available Formats: = Livestream = In Person = On DemandSunday, April 12, 2026
Fundraising
Booking Function
Merchandise Options
Registration Options
Registration
4:00–8:00 PM
Welcome Mixer
6:00–8:00 PM
Monday, April 13, 2026
Breakfast
7:30–8:30 AM
Welcome and Keynote Session
8:30–10:00 AM
Linda G. Griffith, Massachusetts Institute of Technology
Humanizing Drug Discovery: Microphysiological Systems to Model MASH
Humanizing Drug Discovery: Microphysiological Systems to Model MASH
Rohit Loomba, University of California, San Diego, Salk Institute
Translational Update on MASH
Translational Update on MASH
Coffee Break
10:00–10:20 AM
Mechanisms of Hepatocyte Metabolic Dysfunction in Obesity
10:20–11:45 AM
Rotonya Carr, University of Washington
Unraveling the Role of Lipid Droplet Proteins in MASLD
Unraveling the Role of Lipid Droplet Proteins in MASLD
Mark A Herman, Baylor College of Medicine
Carbohydrate Metabolism and Steatosis, Intersection of Hepatokines and Metabolism
Carbohydrate Metabolism and Steatosis, Intersection of Hepatokines and Metabolism
Jennifer L. Estall, Institut de Recherches Cliniques de Montréal
Understanding the Fasting Response in Hepatic Lipid Metabolism
Understanding the Fasting Response in Hepatic Lipid Metabolism
Short Talk(s) Chosen from Abstracts
Poster Setup
11:45–1:00 PM
On Own for Lunch
11:45–5:00 PM
Poster Viewing
1:00–10:00 PM
Symposia Spotlight 1: Late-breaking research presentations selected from abstract submissions
2:30–4:30 PM
Short Talks Chosen from Abstracts
Coffee Available
4:30–5:00 PM
Endocrine Regulators of Hepatocyte Metabolic Functions
5:00–7:00 PM
Magdalene K. Montgomery, University of Melbourne
Using Genome-Wide CRISPR Screens to Identify Novel Regulators of Hepatic Lipid Metabolism in MASH
Using Genome-Wide CRISPR Screens to Identify Novel Regulators of Hepatic Lipid Metabolism in MASH
Kristina Schoonjans, École Polytechnique Fédérale de Lausanne – EPFL
Gut-Liver Axis
Gut-Liver Axis
Timothy P. Rolph, Akero Therapeutics
FGFs in MASH Pathogenesis and Therapy
FGFs in MASH Pathogenesis and Therapy
Filip K. Knop, Gentofte Hospital, University of Copenhagen
Role of Glucagon and Incretins in MASH
Role of Glucagon and Incretins in MASH
Short Talk(s) Chosen from Abstracts
Social Hour with Dinner
7:00–8:00 PM
Posters
7:30–10:00 PM
Tuesday, April 14, 2026
Breakfast
7:30–8:30 AM
Poster Setup
8:00–8:30 AM
Poster Viewing
8:15–5:00 PM
Intercellular and Interorgan Crosstalk in Development of Liver Disease
8:30–11:30 AM
Xingxing Kong, Fudan University
Adipose-Muscle-Liver Crosstalk
Adipose-Muscle-Liver Crosstalk
Ruchi Bansal, University of Twente
Single-Cell Phenomics and EV-Omics to Unravel Cellular and Organ Crosstalk in MASH and Liver Cancer
Single-Cell Phenomics and EV-Omics to Unravel Cellular and Organ Crosstalk in MASH and Liver Cancer
Ornella Barrandon, Cellarity
Revealing Novel MASH Biology at Single Cell Resolution
Revealing Novel MASH Biology at Single Cell Resolution
Short Talk(s) Chosen from Abstracts
Coffee Break
9:30–9:50 AM
Lunch
11:30–12:30 PM
Posters
12:00–2:30 PM
Career Roundtable
3:00–4:30 PM
Coffee Available
4:30–5:00 PM
Intrahepatic Determinants of Liver Inflammation and Fibrosis in MASH
5:00–7:00 PM
Utpal B. Pajvani, Columbia University Medical Center
Adipogenic Reprogramming of Hepatocytes as a Contributor to Fibrosis
Adipogenic Reprogramming of Hepatocytes as a Contributor to Fibrosis
Mathias Florian Heikenwälder, German Cancer Research Center, DKFZ
Fueling MASH: Metabolic Drivers and Inflammatory Crosstalk
Fueling MASH: Metabolic Drivers and Inflammatory Crosstalk
Ariel E. Feldstein, University of California, San Diego & Novo Nordisk
Novel Drivers of the Inflammatory Response in Liver Injury and Fibrosis
Novel Drivers of the Inflammatory Response in Liver Injury and Fibrosis
Short Talk(s) Chosen from Abstracts
On Own for Dinner
7:00–8:00 PM
Wednesday, April 15, 2026
Breakfast
7:30–8:30 AM
Mechanisms of Liver Regeneration and Progression to HCC
8:30–11:30 AM
Hao Zhu, University of Texas Southwestern Medical Center
Somatic Mutations in MASH Progression
Somatic Mutations in MASH Progression
Robert F. Schwabe, Columbia University
Regulation of Hepatocyte Metabolism by Hepatic Stellate Cells in MASH: Looking Beyond Fibrogenesis
Regulation of Hepatocyte Metabolism by Hepatic Stellate Cells in MASH: Looking Beyond Fibrogenesis
KyeongJin Kim, Inha University
Mechanisms of MASH-Induced HCC
Mechanisms of MASH-Induced HCC
Short Talk(s) Chosen from Abstracts
Coffee Break
9:30–9:50 AM
On Own for Lunch
11:30–5:00 PM
Symposia Spotlight 2: Late-breaking research presentations selected from abstract submissions
2:30–4:30 PM
Short Talks Chosen from Abstracts
Coffee Available
4:30–5:00 PM
Emerging Translational Approaches to MASH
5:00–6:45 PM
Simon Cockell, University of Newcastle upon Tyne
Proteo-Transcriptomic Profiles in MASLD
Proteo-Transcriptomic Profiles in MASLD
Diana Julie Leeming, Nordic Bioscience
Circulating Markers of Extracellular Matrix for MASLD Risk Stratification and Prediction of Response to Therapy
Circulating Markers of Extracellular Matrix for MASLD Risk Stratification and Prediction of Response to Therapy
Katy Wack, PathAI
Bringing Precision to Pathologic Assessment for MASH: Clinical Validation of an AI-based Drug Development Tool
Bringing Precision to Pathologic Assessment for MASH: Clinical Validation of an AI-based Drug Development Tool
Short Talk(s) Chosen from Abstracts
Meeting Wrap-Up: Outcomes and Future Directions (Organizers)
6:45–7:00 PM
Social Hour with Dinner
7:00–8:00 PM
Cash Bar
8:00–11:00 PM
Entertainment
8:00–11:00 PM
Thursday, April 16, 2026
Departure
12:00–11:59 PM
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