Microbiome Metabolism and Metabolites: Discovery and Function in Health and Disease
Jan 19–22, 2026 | Fairmont Banff Springs, Banff, AB, Canada
Scientific Organizers:
Pieter Dorrestein, Michael A. Fischbach, Neha Garg, and Ines Thiele
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Jan 19–22, 2026 | Fairmont Banff Springs, Banff, AB, Canada
Scientific Organizers: Pieter Dorrestein, Michael A. Fischbach, Neha Garg, and Ines Thiele
Pieter Dorrestein, PhD
University of California, San Diego
Michael A. Fischbach, PhD
Stanford University
Neha Garg
Georgia Institute of Technology
Ines Thiele, PhD
University of Galway
Available Formats:
Supported by:
In Person
On Demand
***Meeting program subject to change.
Available Formats: = In Person = On DemandMonday, January 19, 2026
Fundraising
Booking Function
Merchandise Options
Registration Options
Registration
4:00–8:00 PM
Riverview Lounge
Welcome Mixer
6:00–8:00 PM
Riverview Lounge
Tuesday, January 20, 2026
Breakfast
7:00–8:00 AM
Alberta/New Brunswick
Welcome and Keynote Session (Joint)
8:00–9:30 AM
Cascade Ballroom
Emily P Balskus, HHMI-Harvard University
Mechanistic Enzymology of Microbiome-Derived Gene Products
Mechanistic Enzymology of Microbiome-Derived Gene Products
Mohamed S. Abou Donia, Princeton University
Production and Metabolism of Bioactive Molecules by the Human Microbiome
Production and Metabolism of Bioactive Molecules by the Human Microbiome
Coffee Break
9:30–9:50 AM
Riverview Lounge
Microbial Biochemistry in Health and Disease (Joint)
10:00–11:30 AM
Cascade Ballroom
Stavroula Hatzios, Yale University
Microbial Modulation of Redox-Active Molecules in the Gut
Microbial Modulation of Redox-Active Molecules in the Gut
Harry Sokol, Saint-Antoine Hospital
Effect of Microbiome on Energy Metabolism in IBD
Effect of Microbiome on Energy Metabolism in IBD
Tamia A Harris-Tryon, University of Texas Southwestern Medical Center
Host-Microbial Crosstalk at the Skin Surface
Host-Microbial Crosstalk at the Skin Surface
Meet the Editors (Joint)
11:15–12:15 PM
Cascade Ballroom
Poster Setup
11:15–1:00 PM
Alberta/New Brunswick
On Own for Lunch
11:15–2:30 PM
Poster Viewing
1:00–10:00 PM
Alberta/New Brunswick
Symposia Spotlight 1
2:30–4:30 PM
Alhambra Ballroom
Angela Sofia Burkhart Colorado, University of Colorado Anschutz Medical Campus
DietMicrobeNet: A Bioinformatics Tool to Increase Resolution of Diet-Microbe Relationships at the Compound-Enzyme Level Using Networks
DietMicrobeNet: A Bioinformatics Tool to Increase Resolution of Diet-Microbe Relationships at the Compound-Enzyme Level Using Networks
Jonas Cremer, Stanford University
Quantifying Metabolic Fluxes from the Gut Microbiota to Human Host
Quantifying Metabolic Fluxes from the Gut Microbiota to Human Host
Jelle Dillen, University of Antwerp
Composition-Driven Discovery of Antimicrobial Metabolites and Peptides From the Vaginal Microbiome
Composition-Driven Discovery of Antimicrobial Metabolites and Peptides From the Vaginal Microbiome
Arvid E Gollwitzer †, Broad
MetaOmics-10T: An Openly Shareable Foundational Dataset to Unlock AI-Accelerated Discovery in Microbial Ecosystems
MetaOmics-10T: An Openly Shareable Foundational Dataset to Unlock AI-Accelerated Discovery in Microbial Ecosystems
Erik Hasenoehrl †, Brigham and Women's Hospital, Boston Children's Hospital
Identification of Key Bacteria, Genes, and Metabolites in the Microbiota-mediated Metabolism of Bilirubin
Identification of Key Bacteria, Genes, and Metabolites in the Microbiota-mediated Metabolism of Bilirubin
Caitlin H Kowalski, Dartmouth Hitchcock Medical Center
Mycobiome-Mediated Lipid Transformations in the Skin Microenvironment
Mycobiome-Mediated Lipid Transformations in the Skin Microenvironment
Andrei Osterman, Stanford Burnham Prebys Medical Discovery Institute
Genomics-Guided Prediction of Microbial Metabolic Phenotypes for Rational Design of Microbiome-Targeted Nutritional Supplements
Genomics-Guided Prediction of Microbial Metabolic Phenotypes for Rational Design of Microbiome-Targeted Nutritional Supplements
Coffee Available
4:30–5:00 PM
Riverview Lounge
Microbiome Metabolites in Immune Regulation and Metabolic Health
5:00–7:00 PM
Alhambra Ballroom
Shana Sturla, ETH Zürich
Impact of the Human Gut Microbiome on Chemical Metabolism and Toxicity
Impact of the Human Gut Microbiome on Chemical Metabolism and Toxicity
Fredrik Bäckhed, University of Gothenburg
Microbiome and Metabolic Signaling in the Gut
Microbiome and Metabolic Signaling in the Gut
Changtao Jiang, Peking University Health Science Center
Unlocking the Potential of Gut Microbial Enzymes for Precision Treatment of Metabolic Diseases
Unlocking the Potential of Gut Microbial Enzymes for Precision Treatment of Metabolic Diseases
Margaret Alexander, University of Wisconsin - Madison
Short Talk: Mechanisms of the Microbiota-Dependent Protective Effect of a Ketogenic Diet in Multiple Sclerosis Models
Short Talk: Mechanisms of the Microbiota-Dependent Protective Effect of a Ketogenic Diet in Multiple Sclerosis Models
Robert Quinn, Michigan State University
Short Talk: Microbially Conjugated Bile Acids as a New Dialect in the Host-Microbiome Crosstalk
Short Talk: Microbially Conjugated Bile Acids as a New Dialect in the Host-Microbiome Crosstalk
Social Hour with Dinner
7:00–8:00 PM
Alberta/New Brunswick
Poster Session 1
7:30–10:00 PM
Alberta/New Brunswick
Wednesday, January 21, 2026
Breakfast
7:00–8:00 AM
Alberta/New Brunswick
Emerging Tools to Study Microbiome Derived Metabolites
8:00–11:00 AM
Alhambra Ballroom
Ines Thiele, University of Galway
Metabolic Models of Microbiome
Metabolic Models of Microbiome
Alexey Melnik, Arome Science Inc.
Quantitative Metabolomics in Microbiome Research
Quantitative Metabolomics in Microbiome Research
Pieter Dorrestein, University of California, San Diego
Speeding up the Process to Discover Microbiome Derived Molecules with Fast Computation, Leveraging Public Data and New Metabolomics Mining Tools
Speeding up the Process to Discover Microbiome Derived Molecules with Fast Computation, Leveraging Public Data and New Metabolomics Mining Tools
Clary B. Clish, Broad Institute of MIT and Harvard
Metabolomics in Human Health
Metabolomics in Human Health
Abigail S Gancz, North Carolina State University
Short Talk: Successful Fecal Microbiota Transplants in Recurrent Clostridioides Difficile Patients Are Associated with Lipidomic Shifts in Acylcarnitines and Sphingolipids with Concurrent Shifts in Enterobacteriaceae
Short Talk: Successful Fecal Microbiota Transplants in Recurrent Clostridioides Difficile Patients Are Associated with Lipidomic Shifts in Acylcarnitines and Sphingolipids with Concurrent Shifts in Enterobacteriaceae
Simone Zuffa, UC San Diego
Short Talk: A Multi-Organ Murine Metabolomics Atlas Reveals Molecular Dysregulations in Alzheimer’s Disease
Short Talk: A Multi-Organ Murine Metabolomics Atlas Reveals Molecular Dysregulations in Alzheimer’s Disease
Coffee Break
9:00–9:20 AM
Riverview Lounge
Poster Setup
11:00–1:00 PM
Alberta/New Brunswick
On Own for Lunch
11:00–3:00 PM
Poster Viewing
1:00–10:00 PM
Alberta/New Brunswick
Career Roundtable (Joint)
2:00–3:30 PM
Alhambra Ballroom
Coffee Break with Hot Chocolate, Firepits & Mountain Views
4:00–5:00 PM
Conservatory Terrace
The Genes that Make Microbial Metabolites
5:00–7:00 PM
Alhambra Ballroom
Marnix Medema, Wageningen University
Elucidating the Functions of Metabolic Gene Clusters in Microbiomes using Computational Omics
Elucidating the Functions of Metabolic Gene Clusters in Microbiomes using Computational Omics
Sloan Devlin, Harvard Medical School
Gut Microbial Chemistry in Health and Disease
Gut Microbial Chemistry in Health and Disease
Karen D Corbin, AdventHealth Translational Research Institute
Microbial Metabolites as Biomarkers and Mechanistic Influencers of Human Energy Balance
Microbial Metabolites as Biomarkers and Mechanistic Influencers of Human Energy Balance
Hannah E Augustijn, Wageningen University & Research
Short Talk: Harnessing Microbial Regulatory Networks to Unlock Biosynthetic Potential
Short Talk: Harnessing Microbial Regulatory Networks to Unlock Biosynthetic Potential
Caroline E Dricot, University of Antwerp
Short Talk: Microdiversity in the Shadows: Functional Specialization and SNP-Driven Overproduction of Vitamins and Indoles in Vaginal Limosilactobacillus
Short Talk: Microdiversity in the Shadows: Functional Specialization and SNP-Driven Overproduction of Vitamins and Indoles in Vaginal Limosilactobacillus
Social Hour with Dinner
7:00–8:00 PM
Alberta/New Brunswick
Poster Session 2
7:30–10:00 PM
Alberta/New Brunswick
Thursday, January 22, 2026
Breakfast
7:00–8:00 AM
Alberta/New Brunswick
Advanced Methods to Study the Microbiome (Joint)
8:00–11:00 AM
Cascade Ballroom
Donald E. Ingber, Wyss Institute for Biologically Inspired Engineering at Harvard
Studying the Vaginal Microbiome with Organ-on-a-Chip Methods
Studying the Vaginal Microbiome with Organ-on-a-Chip Methods
Jared Kehe, Concerto Biosciences
Measuring Millions of Microbial Combinations to Unravel the Ecology of the Skin Microbiome
Measuring Millions of Microbial Combinations to Unravel the Ecology of the Skin Microbiome
Elaine Y. Hsiao, University of California, Los Angeles
Advances in the Gut-Brain Axis
Advances in the Gut-Brain Axis
Diego R Gelsinger, Columbia University
Short Talk: Metagenomic Editing of Commensal Bacteria in vivo using CRISPR-associated Transposases
Short Talk: Metagenomic Editing of Commensal Bacteria in vivo using CRISPR-associated Transposases
Nick Burton, Van Andel Institute
Short Talk: A High-Throughput Screening Platform for Identifying Microbiome Produced Metabolites that Regulate Animal Physiology
Short Talk: A High-Throughput Screening Platform for Identifying Microbiome Produced Metabolites that Regulate Animal Physiology
Coffee Break
9:00–9:20 AM
Riverview Lounge
Award Recipient Acknowledgement
9:20–9:25 AM
Cascade Ballroom
On Own for Lunch
11:00–2:30 PM
Symposia Spotlight 2
2:30–4:30 PM
Alhambra Ballroom
Tatiana T Marquez-Lago †, University of Alabama at Birmingham, Heersink School of Medicine
Human Milk Microbiome-Metabolome Interactions Influence Cytomegalovirus Transmission to Infants
Human Milk Microbiome-Metabolome Interactions Influence Cytomegalovirus Transmission to Infants
Jared R Mayers, Fred Hutchinson Cancer Center
Leveraging A Reverse-Translational Framework to Decode In Vivo Microbial Metabolism
Leveraging A Reverse-Translational Framework to Decode In Vivo Microbial Metabolism
Aleksandra Uryga, International Institute of Molecular and Cell Biology in Warsaw - IIMCB
Mapping Microbial Metabolites Beyond the Intestine
Mapping Microbial Metabolites Beyond the Intestine
Gaohua Yang, Wallenberg Laboratory, Sahlgrenska University Hospital
A Microbial Caffeic Acid To 4-Ethylcatechol Funnel In Polyphenol Catabolism Protects Against Diet-Induced Hepatic Steatosis
A Microbial Caffeic Acid To 4-Ethylcatechol Funnel In Polyphenol Catabolism Protects Against Diet-Induced Hepatic Steatosis
Jacqueline A Barnett, Melius MicroBiomics
Rational Engineering of Escherichia coli Nissle 1917 for Inflammation-Selective Expansion Enables Single-Dose Therapeutic Efficacy and Systemic Metabolic Remodeling in a Translational Porcine Colitis Model
Rational Engineering of Escherichia coli Nissle 1917 for Inflammation-Selective Expansion Enables Single-Dose Therapeutic Efficacy and Systemic Metabolic Remodeling in a Translational Porcine Colitis Model
Camilo Anthony G Gacasan †, Emory University School of Medicine
Beneficial Microbe Driven Rewiring of Metabolic Pathways in the Gut and Liver
Beneficial Microbe Driven Rewiring of Metabolic Pathways in the Gut and Liver
Chayanika Gogoi †, National Institute of Immunology
Nutrient-Driven Microbiome Adaptations Mitigate Salmonella Burden in Mice
Nutrient-Driven Microbiome Adaptations Mitigate Salmonella Burden in Mice
Coffee Available
4:30–5:00 PM
Riverview Lounge
The Metabolism at the Intersection of Microbiome, Host, Drugs and Pathogens
5:00–6:45 PM
Alhambra Ballroom
Casey Michelle Theriot, North Carolina State University
Bile Salt Hydrolases as Regulators of C. difficile Colonization in the Gut
Bile Salt Hydrolases as Regulators of C. difficile Colonization in the Gut
Neha Garg, Georgia Institute of Technology
A Metabolomics Approach to Dissect Interactions between the Pathogen, the Beneficial Bacteria, and the Host
A Metabolomics Approach to Dissect Interactions between the Pathogen, the Beneficial Bacteria, and the Host
Karen L. Madsen, University of Alberta
Talk Title to be Annonced
Talk Title to be Annonced
Michael Zimmermann †, European Molecular Biology Laboratory
Short Talk: Gut Bacteria Generate Prodrugs in situ Increasing Systemic Drug Exposure
Short Talk: Gut Bacteria Generate Prodrugs in situ Increasing Systemic Drug Exposure
Meeting Wrap-Up: Outcomes and Future Directions (Organizers)
6:45–7:00 PM
Alhambra Ballroom
Social Hour with Dinner
7:00–8:00 PM
Alberta/New Brunswick
Entertainment
8:00–9:00 PM
Cash Bar
8:00–9:00 PM
Friday, January 23, 2026
Departure
12:00–11:59 PM
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